Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

36 questions · 36 findings · 2 reviews

No studies found 15 · 41.7%GRADE not reported 5 · 13.9%Very low 7 · 19.4%Low 8 · 22.2%Moderate 1 · 2.8%High 0 · 0%

PIMOZIDE vs placebo

Global state: relapse medium term (3‐12 months) Clinical diagnoses · patients with schizophrenia or related psychoses

It is very uncertain whether PIMOZIDE changes global state: relapse medium term (3‐12 months) Clinical diagnoses compared with PLACEBO (very low certainty).

1 finding from 1 review

PIMOZIDE vs antipsychotics

Mental state: presence of first‐rank symptoms medium term (3‐12 months) Clinical diagnoses · patients with schizophrenia or related psychoses

PIMOZIDE showed no clear difference in mental state: presence of first‐rank symptoms medium term (3‐12… compared with ANY ANTIPSYCHOTIC (low certainty).

1 finding from 1 review

PIMOZIDE vs antipsychotics

Adverse effects: extrapyramidal adverse effectsParkinsonism (rigidity) short term (< 3 months) Clinical diagnoses · patients with schizophrenia or related psychoses

PIMOZIDE showed no clear difference in adverse effects: extrapyramidal adverse effectsParkinsonism… compared with ANY ANTIPSYCHOTIC (low certainty).

1 finding from 1 review

PIMOZIDE vs antipsychotics

Adverse effects: extrapyramidal adverse effects Parkinsonism (tremor) medium term (< 3 months) Clinical diagnoses · patients with schizophrenia or related psychoses

PIMOZIDE showed no clear difference in adverse effects: extrapyramidal adverse effects Parkinsonism… compared with ANY ANTIPSYCHOTIC (low certainty).

1 finding from 1 review

PIMOZIDE vs antipsychotics

Quality of life: no significant change in quality of life/satisfaction medium term (3‐12 months) not reported · patients with schizophrenia or related psychoses

The review found no eligible studies for this question.

1 finding from 1 review

PIMOZIDE vs placebo

Mental state: no improvement medium term (3‐12 months) not reported · patients with schizophrenia or related psychoses

The review found no eligible studies for this question.

1 finding from 1 review

PIMOZIDE vs placebo

Mental state: presence of first‐rank symptoms medium term (3‐12 months) not reported · patients with schizophrenia or related psychoses

The review found no eligible studies for this question.

1 finding from 1 review

PIMOZIDE vs placebo

Adverse effects: extrapyramidal adverse effects Parkinsonism (rigidity) short term (< 3 months) Extrapyramidal Symptom Rating Scale (ESRS) · patients with schizophrenia or related psychoses

It is very uncertain whether PIMOZIDE changes adverse effects: extrapyramidal adverse effects: Parkinsonism… compared with PLACEBO (very low certainty).

1 finding from 1 review

PIMOZIDE vs placebo

Adverse effects: extrapyramidal adverse effects Parkinsonism (rigidity) medium term (3‐12 months) Clinical diagnoses · patients with schizophrenia or related psychoses

It is very uncertain whether PIMOZIDE changes adverse effects: extrapyramidal adverse effects:Parkinsonism… compared with PLACEBO (very low certainty).

1 finding from 1 review

PIMOZIDE vs placebo

Adverse effects: extrapyramidal adverse effects:Parkinsonism (tremor) medium term (3‐12 months) Clinical diagnoses · patients with schizophrenia or related psychoses

It is very uncertain whether PIMOZIDE changes adverse effects: extrapyramidal adverse effects:Parkinsonism… compared with PLACEBO (very low certainty).

1 finding from 1 review

PIMOZIDE vs placebo

Quality of life: no significant change in quality of life/satisfaction medium term (3‐12 months) not reported · patients with schizophrenia or related psychoses

The review found no eligible studies for this question.

1 finding from 1 review

PIMOZIDE vs antipsychotics

Global state: relapse medium term (3‐12 months) Clinical diagnoses · patients with schizophrenia or related psychoses

PIMOZIDE showed no clear difference in global state: relapse medium term (3‐12 months) Clinical diagnoses compared with ANY ANTIPSYCHOTIC (moderate certainty).

1 finding from 1 review

PIMOZIDE vs antipsychotics

Mental state: no improvement medium term (3‐12 months) not reported · patients with schizophrenia or related psychoses

It is very uncertain whether PIMOZIDE changes mental state: no improvement medium term (3‐12 months) As defined in… compared with ANY ANTIPSYCHOTIC (very low certainty).

1 finding from 1 review

PIMOZIDE + ANY ANTIPSYCHOTIC vs antipsychotics

Global state: relapse medium term (3‐12 months) Clinical diagnoses · patients with schizophrenia or related psychoses

PIMOZIDE + ANY ANTIPSYCHOTIC may leads to lower global state: relapsemedium term (3‐12 months) Clinical diagnoses compared with ANY ANTIPSYCHOTIC (low certainty).

1 finding from 1 review