Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Headline outcomes only

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No studies found 0 · 0%GRADE not reported 2 · 28.6%Very low 5 · 71.4%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Antidepressants vs placebo

Depression: meeting study criteria for depression at end of · people with stroke

It is very uncertain whether pharmacological interventions (antidepressants) changes depression: meeting study criteria for depression at end treatment… compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological, psychological and non‐invasive brain stimulation interventions for preventing depression after stroke 2020 · Cochrane Headline outcomes only
RR 0.5 [0.37, 0.68]
9 studies · 734 participants
Very low

Antidepressants vs placebo

Scoring above cut‐off points for a depressive disorder at end of treatment (Analysis 1.2) · people with stroke

1 finding from 1 review

Pharmacological, psychological and non‐invasive brain stimulation interventions for preventing depression after stroke 2020 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Antidepressants vs placebo

Depression: mean scores at end of treatment (Analysis 1.4) · people with stroke

1 finding from 1 review

Pharmacological, psychological and non‐invasive brain stimulation interventions for preventing depression after stroke 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 100 participants
Very low

Antidepressants vs placebo

Cognition at end of treatment · people with stroke

1 finding from 1 review

Pharmacological, psychological and non‐invasive brain stimulation interventions for preventing depression after stroke 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 48 participants
Very low

Antidepressants vs placebo

Activities of daily living · people with stroke

1 finding from 1 review

Pharmacological, psychological and non‐invasive brain stimulation interventions for preventing depression after stroke 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 116 participants
Very low

Antidepressants vs placebo

Disability: mean scores at end of treatment (Analysis 1.10) · people with stroke

1 finding from 1 review

Pharmacological, psychological and non‐invasive brain stimulation interventions for preventing depression after stroke 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 204 participants
GRADE not reported

Antidepressants vs placebo

Adverse events: death ‐ at end of treatment (Analysis 1.14) · people with stroke

It is very uncertain whether pharmacological interventions (antidepressants) changes adverse events: death ‐ at end of treatment Analysis 1.12 compared with placebo (very low certainty).

1 finding from 1 review

Pharmacological, psychological and non‐invasive brain stimulation interventions for preventing depression after stroke 2020 · Cochrane Headline outcomes only
RR 1.25 [0.32, 4.91]
9 studies · 496 participants
Very low