Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

25 questions · 25 findings · 1 reviews · Gynaecology and Fertility

No studies found 6 · 24%GRADE not reported 0 · 0%Very low 15 · 60%Low 4 · 16%Moderate 0 · 0%High 0 · 0%

Pharmacological interventions vs pharmacological intervention

Adverse events ‐ Metformin plus liraglutide vs metformin Nausea Diarrhoea Headache · obese women with subfertility

It is very uncertain whether pharmacological intervention changes adverse events ‐ Metformin plus liraglutide vs metformin Nausea… compared with pharmacological intervention (very low certainty).

1 finding from 1 review

Pharmacological interventions vs pharmacological intervention

Clinical pregnancyMetformin plus liraglutide vs metformin Met + CC + L‐carnitine vs Met + CC + placebo · obese women with subfertility

It is very uncertain whether pharmacological intervention changes clinical pregnancyMetformin plus liraglutide vs metformin Met + CC +… compared with pharmacological intervention (very low certainty).

1 finding from 1 review

Pharmacological interventions vs pharmacological intervention

MiscarriageMet + CC + L‐carnitine vs Met + CC + placebo · obese women with subfertility

It is very uncertain whether pharmacological intervention changes miscarriageMet + CC + L‐carnitine vs Met + CC + placebo compared with pharmacological intervention (very low certainty).

1 finding from 1 review

Pharmacological interventions vs pharmacological intervention

Weight ‐ BMI changeMetformin plus liraglutide vs metformin Met + CC + L‐carnitine vs Met + CC + placebo Weight changeDexfenfluramine vs placebo Weight ‐ body fatMetformin plus liraglutide vs metformin · obese women with subfertility
1 finding from 1 review