What do systematic reviews say?

Oral immunosuppressants: oral cyclosporin vs topical betamethasone dipropionate

Oral immunosuppressants: oral cyclosporin showed no clear difference in primary: investigator‐ rated good/excellent control of symptomsb compared with topical betamethasone dipropionate (moderate certainty).

• Interventions for hand eczema 2019 · Cochrane Headline outcomes only
  RR 1.88 [0.88, 3.99]
  1 study · 34 participants
  Moderate

Oral immunosuppressants: oral cyclosporin vs topical betamethasone dipropionate

Oral immunosuppressants: oral cyclosporin showed no clear difference in primary: participant‐rated good/excellent control of symptomsb compared with topical betamethasone dipropionate (moderate certainty).

• Interventions for hand eczema 2019 · Cochrane Headline outcomes only
  RR 1.25 [0.69, 2.27]
  1 study · 34 participants
  Moderate

Oral immunosuppressants: oral cyclosporin vs topical betamethasone dipropionate

Oral immunosuppressants: oral cyclosporin showed no clear difference in primary: adverse events ‐ at least 1 adverse event compared with topical betamethasone dipropionate (moderate certainty).

• Interventions for hand eczema 2019 · Cochrane Headline outcomes only
  RR 1.22 [0.8, 1.86]
  1 study · 55 participants
  Moderate

Oral immunosuppressants: oral cyclosporin vs topical betamethasone dipropionate

• Interventions for hand eczema 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 34 participants
  Moderate

Summary of findings table ‐ Oral classical immunosuppressants (prednisolone or cyclosporine) vs placebo

It is very uncertain whether summary of findings table ‐ Oral classical immunosuppressants… changes short‐term hair regrowth ≥ 75% (between 12 and 26 weeks of compared with placebo (very low certainty).

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  RR 4.68 [0.57, 38.27]
  2 studies · 79 participants
  Very low

Summary of findings table ‐ Oral classical immunosuppressants (prednisolone or cyclosporine) vs placebo

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 79 participants
  Very low

Summary of findings table ‐ Oral classical immunosuppressants (prednisolone or cyclosporine) vs placebo

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 36 participants
  Very low

Summary of findings table ‐ Oral classical immunosuppressants (prednisolone or cyclosporine) vs placebo

The review found no eligible studies for this question.

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found