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Evidence found and GRADE certainty

1,809 questions · 1,956 findings · 194 reviews

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No studies found 422 · 21.6%GRADE not reported 427 · 21.8%Very low 353 · 18%Low 397 · 20.3%Moderate 293 · 15%High 64 · 3.3%

Summary of findings: intranasal steroids plus oral antibiotic vs control plus antibiotic

OME resolution at intermediate‐term · Children with otitis media with effusion

Summary of findings: intranasal steroids plus oral antibiotic showed no clear difference in OME resolution at intermediate‐term compared with control plus antibiotic (moderate certainty).

1 finding from 1 review

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care vs placebo or usual care

Incidence of VAP · Critically ill patients (adults and children) receiving mechanical ventilation in ICU

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care probably leads to lower incidence of VAP compared with placebo or usual care (moderate certainty).

1 finding from 1 review

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care vs placebo or usual care

Adverse effects · Critically ill patients (adults and children) receiving mechanical ventilation in ICU
1 finding from 1 review

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care vs placebo or usual care

All‐cause mortality · Critically ill patients (adults and children) receiving mechanical ventilation in ICU

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care showed no clear difference in mortality compared with placebo or usual care (moderate certainty).

1 finding from 1 review

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care vs placebo or usual care

Duration of mechanical ventilation · Critically ill patients (adults and children) receiving mechanical ventilation in ICU

It is very uncertain whether chlorhexidine (mouthrinse or gel), as part of oral hygiene care changes duration of mechanical ventilation compared with placebo or usual care (very low certainty).

1 finding from 1 review

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care vs placebo or usual care

Duration of ICU stay · Critically ill patients (adults and children) receiving mechanical ventilation in ICU

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care showed no clear difference in duration of ICU stay compared with placebo or usual care (low certainty).

1 finding from 1 review

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care vs placebo or usual care

Duration of systemic antibiotic use · Critically ill patients (adults and children) receiving mechanical ventilation in ICU

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care showed no clear difference in duration of systemic antibiotic use compared with placebo or usual care; GRADE not reported.

1 finding from 1 review

Community and caregiver oral health education plus media campaign vs Pre-intervention BBTD rate

Baby bottle tooth decay prevalence · Alaska Native and American Indian Head Start children

High-intensity community education was associated with a 33% reduction in BBTD prevalence, without a GRADE rating.

3 findings from 1 review

Community and caregiver oral health education plus media campaign vs Pre-intervention BBTD rate

Baby bottle tooth decay prevalence · Alaska Native Head Start children

The Alaska Native site had a 20% increase in BBTD prevalence, without a GRADE rating.

1 finding from 1 review

Visual screening (oral visual inspection) by trained health workers vs No screening

Costs · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of Trivandrum city, Kerala,…
1 finding from 1 review
  • Screening programmes for the early detection and prevention of oral cancer 2013 · Cochrane All outcomes
    9 years (three cycles)
    The costs associated with the screening programme were reported after three cycles (nine years) (Subramanian 2009) (Additional Table 8). The benefit produced by a screen was 269.31 life-years saved per 100,000 for all…
    1 study
    GRADE not reported

Visual screening (oral visual inspection) by trained health workers vs No screening

Harms of screening (false-positive/false-negative outcomes) · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of Trivandrum city, Kerala,…

The review found no eligible studies for this question.

1 finding from 1 review

Visual screening (oral visual inspection) by trained health workers vs No screening

Stage at diagnosis (early-stage detection) · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of Trivandrum city, Kerala,…

Visual screening (oral visual inspection) by trained health workers led to lower stage at diagnosis (early-stage detection) compared with no screening; GRADE not reported.

2 findings from 1 review

Visual screening (oral visual inspection) by trained health workers vs No screening

Quality of life · Apparently healthy adults aged 35 years or older (general population), living in 13 clusters in rural areas of Trivandrum city, Kerala,…

The review found no eligible studies for this question.

1 finding from 1 review