Findings

What do systematic reviews say?

81 questions · 92 findings · 8 reviews

No studies found 29 · 31.5%GRADE not reported 1 · 1.1%Very low 27 · 29.3%Low 22 · 23.9%Moderate 10 · 10.9%High 3 · 3.3%

Withdrawal symptoms · Patients with osteoarthritis of the knee or hip

Oral or transdermal opioids probably leads to higher withdrawal symptoms (median compared with placebo (moderate certainty).

1 finding from 1 review

Oral or transdermal opioids for osteoarthritis of the knee or hip 2014 · Cochrane Headline outcomes only
OR 2.67 [2.02, 3.77]
3 studies · 1151 participants
Moderate