Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

22 questions · 23 findings · 3 reviews

No studies found 10 · 43.5%GRADE not reported 2 · 8.7%Very low 4 · 17.4%Low 7 · 30.4%Moderate 0 · 0%High 0 · 0%

Opioid antagonists vs placebo

Nausea · preventing nausea and vomiting
2 findings from 1 review

Opioid antagonists vs placebo

Treatment responseaClinical Global Impressions ‐ Improvement Scale (CGI‐I) (no. of responders) & NIMH Trichotillomania Severity Scale (NIMH‐TSS) (no. of responders as > 50% reduction) · adults with trichotillomania

It is very uncertain whether opioid antagonists changes treatment responseaClinical Global Impressions ‐ Improvement Scale… compared with placebo (very low certainty).

1 finding from 1 review