Ocriplasmin injection leads to higher complete release of vitreous adhesion compared with control (high certainty).
Ocriplasmin injection leads to higher closure of macular hole compared with control (high certainty).
Ocriplasmin injection leads to higher complete posterior vitreous detachment compared with control (high certainty).
Ocriplasmin injection probably leads to higher 3‐line or greater improvement in best‐corrected visual acuity compared with control (moderate certainty).
Ocriplasmin injection probably leads to lower requirement for vitrectomy compared with control (moderate certainty).
Ocriplasmin injection probably leads to higher any ocular adverse event compared with control (moderate certainty).