Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

16 questions · 16 findings · 2 reviews

No studies found 4 · 25%GRADE not reported 0 · 0%Very low 6 · 37.5%Low 3 · 18.8%Moderate 0 · 0%High 3 · 18.8%

NSAIDs vs placebo or no treatment

AKI within 30 days of surgery · adults with normal kidney function undergoing surgery

It is very uncertain whether nonsteroidal anti‐inflammatory drugs (NSAIDs) changes AKI within 30 days of surgery compared with placebo or no treatment (very low certainty).

1 finding from 1 review

NSAIDs vs placebo or no treatment

RRT within 30 days of surgery · adults with normal kidney function undergoing surgery

It is very uncertain whether nonsteroidal anti‐inflammatory drugs (NSAIDs) changes RRT within 30 days of surgery compared with placebo or no treatment (very low certainty).

1 finding from 1 review

NSAIDs vs control or placebo medications

Adverse event nausea and vomiting (0 to 24 hours) · adults undergoing brain surgery

Nonsteroidal anti‐inflammatory drugs (NSAIDs) showed no clear difference in adverse event nausea and vomiting (0 to 24 hours) compared with control or placebo medications (low certainty).

1 finding from 1 review

NSAIDs vs placebo or no treatment

Death (all causes) · adults with normal kidney function undergoing surgery

It is very uncertain whether nonsteroidal anti‐inflammatory drugs (NSAIDs) changes death (all causes) compared with placebo or no treatment (very low certainty).

1 finding from 1 review

NSAIDs vs placebo or no treatment

Length of hospital stay · adults with normal kidney function undergoing surgery

It is very uncertain whether nonsteroidal anti‐inflammatory drugs (NSAIDs) changes length of hospital stay compared with placebo or no treatment (very low certainty).

1 finding from 1 review