Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

28 questions · 28 findings · 2 reviews

No studies found 1 · 3.6%GRADE not reported 4 · 14.3%Very low 8 · 28.6%Low 6 · 21.4%Moderate 9 · 32.1%High 0 · 0%

HFNC vs continuous positive airway pressure (CPAP)

Treatment failure · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))

It is very uncertain whether summary of findings table ‐ High flow nasal cannula (HFNC) changes treatment failure compared with continuous positive airway pressure (CPAP) (very low certainty).

1 finding from 1 review

HFNC vs continuous positive airway pressure (CPAP)

Adverse events ‐ nasal trauma · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))

It is very uncertain whether summary of findings table ‐ High flow nasal cannula (HFNC) changes adverse events ‐ nasal trauma compared with continuous positive airway pressure (CPAP) (very low certainty).

1 finding from 1 review

HFNC vs continuous positive airway pressure (CPAP)

Adverse events ‐ abdominal overdistention · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))

It is very uncertain whether summary of findings table ‐ High flow nasal cannula (HFNC) changes adverse events ‐ abdominal overdistention compared with continuous positive airway pressure (CPAP) (very low certainty).

1 finding from 1 review

HFNC vs low flow nasal cannula (LFNC)

Treatment failure · respiratory support in term infants (infants ≥ 37 weeks gestational age to the end of the neonatal period (up to 1 month postnatal age))

Summary of findings table ‐ High flow nasal cannula (HFNC) may leads to lower treatment failure compared with low flow nasal cannula (LFNC) (low certainty).

1 finding from 1 review