Findings

What do systematic reviews say?

23 questions · 24 findings · 4 reviews

No studies found 10 · 41.7%GRADE not reported 4 · 16.7%Very low 3 · 12.5%Low 6 · 25%Moderate 1 · 4.2%High 0 · 0%

Safety of the intervention (adverse effects) · People with a diagnosis of oral leukoplakia

1 finding from 1 review

Interventions for treating oral leukoplakia to prevent oral cancer 2016 · Cochrane All outcomes
over 3 months
SoF 3, Safety of the intervention over 3 months: systemic celecoxib (1 study) - 32 intervention participants reported 56 adverse effects, 20 placebo participants reported 20; 4 grade 3 events; 2 discontinued. Ketorolac…
2 studies
GRADE not reported

Improvement of histological features (not improved) · People with a diagnosis of oral leukoplakia

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating oral leukoplakia to prevent oral cancer 2016 · Cochrane All outcomes
SoF 3, Histological changes: 'Not measured'. Effects text: 'Histological changes were not among the outcomes in the studies testing NSAIDs.'
0 studies
No studies found

Rescue analgesia · analgesia in traumatic corneal abrasions

Topical NSAIDs may leads to lower use of rescue oral analgesia at 24 hours compared with control (low certainty).

2 findings from 1 review

Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions 2017 · Cochrane Headline outcomes only
RR 0.46 [0.34, 0.61]
4 studies · 481 participants
Low
Topical non‐steroidal anti‐inflammatory drugs for analgesia in traumatic corneal abrasions 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found