Findings

What do systematic reviews say?

9 questions · 9 findings · 2 reviews · Back and Neck

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 4 · 44.4%Low 3 · 33.3%Moderate 1 · 11.1%High 1 · 11.1%

Closest answers

The findings closest to your search, judged one by one by TypeSafe's Jev model.

Direct match · question page
- NSAIDs vs placebo · Pain intensity VAS (0 to 100; lower = better)
  Non‐steroidal anti‐inflammatory drugs for acute low back pain 2020 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 815 participants
  Moderate
Direct match · question page
- NSAIDs vs placebo · Proportion of participants experiencing global improvement Various dichotomised Likert scales; lower = better
  Non‐steroidal anti‐inflammatory drugs for acute low back pain 2020 · Cochrane Headline outcomes only
  RR 1.4 [1.12, 1.75]
  5 studies · 1201 participants
  Low
Direct match · question page
- NSAIDs vs placebo · Change in pain intensity from baseline on VAS (0 to 100) short‐term
  Non‐steroidal anti‐inflammatory drugs for sciatica 2016 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 918 participants
  Very low
Direct match · question page
- NSAIDs vs placebo · Disability RMDQ (0 to 24; lower = better)
  Non‐steroidal anti‐inflammatory drugs for acute low back pain 2020 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 471 participants
  High
Direct match · question page
- NSAIDs vs placebo · Change in disability from baseline to
  Non‐steroidal anti‐inflammatory drugs for sciatica 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 214 participants
  Very low

NSAIDs vs placebo

Pain intensity VAS (0 to 100; 0 = no pain, 100 = worst pain) · Patients with acute low‐back pain

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs for acute low back pain 2020 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 815 participants
Moderate

NSAIDs vs placebo

Disability RMDQ (0 to 24; lower = better) · Patients with acute low‐back pain

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs for acute low back pain 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 471 participants
High

NSAIDs vs placebo

Proportion of participants experiencing global improvement % of dichotomized Likert scale · Patients with acute low‐back pain

NSAIDs may leads to higher proportion of participants experiencing global improvement Various… compared with placebo (low certainty).

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs for acute low back pain 2020 · Cochrane Headline outcomes only
RR 1.4 [1.12, 1.75]
5 studies · 1201 participants
Low

NSAIDs vs placebo

Proportion of participants experiencing adverse events · Patients with acute low‐back pain

It is very uncertain whether NSAIDs changes proportion of participants experiencing adverse events compared with placebo (very low certainty).

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs for acute low back pain 2020 · Cochrane Headline outcomes only
RR 0.86 [0.63, 1.18]
6 studies · 1394 participants
Very low

NSAIDs vs placebo

Return to work · Patients with acute low‐back pain

It is very uncertain whether NSAIDs changes return to work (%) compared with placebo (very low certainty).

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs for acute low back pain 2020 · Cochrane Headline outcomes only
RR 1.48 [0.98, 2.23]
1 study · 266 participants
Very low

NSAIDs vs placebo

Change in pain intensity from baseline on VAS (0 to 100) short‐term · people with low back pain with sciatica

It is very uncertain whether NSAIDs changes change in pain intensity from baseline on VAS (0 to 100) short‐term compared with placebo (very low certainty).

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs for sciatica 2016 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 918 participants
Very low

NSAIDs vs placebo

Change in disability from baseline to · people with low back pain with sciatica

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs for sciatica 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 214 participants
Very low

NSAIDs vs placebo

Global Improvement short‐term · people with low back pain with sciatica

NSAIDs may leads to higher global Improvement short‐term compared with placebo (low certainty).

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs for sciatica 2016 · Cochrane Headline outcomes only
RR 1.14
3 studies · 753 participants
Low

NSAIDs vs placebo

Side effects short‐term · people with low back pain with sciatica

NSAIDs may leads to higher side effects short‐term compared with placebo (low certainty).

1 finding from 1 review

Non‐steroidal anti‐inflammatory drugs for sciatica 2016 · Cochrane Headline outcomes only
RR 1.4
4 studies · 967 participants
Low