NSAIDs vs other analgesics
- Perioperative systemic nonsteroidal anti‐inflammatory drugs (NSAIDs) in women undergoing breast surgery 2021 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 178 participantsLow
It is very uncertain whether NSAID changes incidence of breast hematoma within 90 days of breast surgery compared with other analgesic (very low certainty).
NSAID showed no clear difference in incidence of breast hematoma compared with placebo (low certainty).
NSAID probably leads to lower incidence rate or severity of postoperative nausea, vomiting, or both compared with other analgesic (moderate certainty).
It is very uncertain whether NSAID changes bleeding from any location within 90 days compared with other analgesic (very low certainty).
It is very uncertain whether NSAID changes other side effects of NSAID use compared with other analgesic (very low certainty).
NSAID showed no clear difference in incidence rate or severity of postoperative nausea, vomiting, or both compared with placebo (low certainty).
NSAID showed no clear difference in bleeding from any location within 90 days compared with placebo (low certainty).
It is very uncertain whether NSAID changes need for blood transfusion compared with placebo (very low certainty).
NSAID showed no clear difference in other side effects of NSAID use compared with placebo (low certainty).