Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Pain, Palliative and Supportive Care

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 7 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

NSAIDs vs placebo

Substantial benefit: At least 50% reduction in pain, or PGIC much improved · adults with fibromyalgia

It is very uncertain whether NSAID changes substantial pain relief: at least 50% reduction in pain, or PGIC… compared with placebo (very low certainty).

1 finding from 1 review

Oral nonsteroidal anti‐inflammatory drugs for fibromyalgia in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 146 participants
Very low

NSAIDs vs placebo

Moderate benefit: At least 30% reduction in pain, or PGIC much or very much improved · adults with fibromyalgia

It is very uncertain whether NSAID changes moderate pain relief: at least 30% reduction in pain, or PGIC much… compared with placebo (very low certainty).

1 finding from 1 review

Oral nonsteroidal anti‐inflammatory drugs for fibromyalgia in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 192 participants
Very low

NSAIDs vs placebo

Serious adverse events · adults with fibromyalgia

1 finding from 1 review

Oral nonsteroidal anti‐inflammatory drugs for fibromyalgia in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

NSAIDs vs placebo

Withdrawals due to adverse events · adults with fibromyalgia

It is very uncertain whether NSAID changes adverse event withdrawal compared with placebo (very low certainty).

1 finding from 1 review

Oral nonsteroidal anti‐inflammatory drugs for fibromyalgia in adults 2017 · Cochrane Headline outcomes only
RD 0.04
4 studies · 230 participants
Very low

NSAIDs vs placebo

Number experiencing adverse effects · adults with fibromyalgia

It is very uncertain whether NSAID changes participants experiencing any adverse event compared with placebo (very low certainty).

1 finding from 1 review

Oral nonsteroidal anti‐inflammatory drugs for fibromyalgia in adults 2017 · Cochrane Headline outcomes only
RD 0.08
4 studies · 230 participants
Very low

NSAIDs vs placebo

Withdrawal (all‐cause) · adults with fibromyalgia

It is very uncertain whether NSAID changes all cause withdrawal compared with placebo (very low certainty).

1 finding from 1 review

Oral nonsteroidal anti‐inflammatory drugs for fibromyalgia in adults 2017 · Cochrane Headline outcomes only
RD 0.03
3 studies · 192 participants
Very low

NSAIDs vs placebo

Death · adults with fibromyalgia

1 finding from 1 review

Oral nonsteroidal anti‐inflammatory drugs for fibromyalgia in adults 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low