Findings

What do systematic reviews say?

8 questions · 8 findings · 1 reviews · Headline outcomes only

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 12.5%Low 7 · 87.5%Moderate 0 · 0%High 0 · 0%

Overall survival · people receiving allogeneic hematopoietic stem cell transplantation

Mycophenolate mofetil showed no clear difference in overall survival compared with methotrexate (low certainty).

1 finding from 1 review

Prevention of acute GVHD grade II to IV · people receiving allogeneic hematopoietic stem cell transplantation

It is very uncertain whether mycophenolate mofetil changes prevention of acute GVHD grade II to IV compared with methotrexate (very low certainty).

1 finding from 1 review

Relapse · people receiving allogeneic hematopoietic stem cell transplantation

Mycophenolate mofetil showed no clear difference in incidence of relapse compared with methotrexate (low certainty).

1 finding from 1 review

Nonrelapse mortality · people receiving allogeneic hematopoietic stem cell transplantation

Mycophenolate mofetil showed no clear difference in nonrelapse mortality compared with methotrexate (low certainty).

1 finding from 1 review

Prevention of chronic GVHD · people receiving allogeneic hematopoietic stem cell transplantation

Mycophenolate mofetil showed no clear difference in prevention of chronic GVHD compared with methotrexate (low certainty).

1 finding from 1 review

Incidence of severe mucositis · people receiving allogeneic hematopoietic stem cell transplantation

Mycophenolate mofetil may leads to lower incidence of severe mucositis compared with methotrexate (low certainty).

1 finding from 1 review

Use of total parenteral nutrition · people receiving allogeneic hematopoietic stem cell transplantation

Mycophenolate mofetil may leads to lower use of total parenteral nutrition compared with methotrexate (low certainty).

1 finding from 1 review

Incidence of narcotic use for pain control · people receiving allogeneic hematopoietic stem cell transplantation

Mycophenolate mofetil may leads to lower incidence of narcotic use for pain control compared with methotrexate (low certainty).

1 finding from 1 review