Muscle relaxant vs control
Pain ‐ 24hrs (Single dose) · patients with pain management in rheumatoid arthritis
1 finding from 1 review
- no estimate extracted3 studies · 104 participantsLow
Findings
What do systematic reviews say?
8 questions · 8 findings · 2 reviews
No studies found 0 · 0%GRADE not reported 2 · 25%Very low 5 · 62.5%Low 1 · 12.5%Moderate 0 · 0%High 0 · 0%
Muscle relaxant vs control
Pain ‐ 1‐2 weeks · patients with pain management in rheumatoid arthritis
1 finding from 1 review
- no estimate extracted3 studies · 104 participantsVery low
Muscle relaxant vs control
Withdrawals due to adverse events · patients with pain management in rheumatoid arthritis
It is very uncertain whether muscle relaxant changes withdrawal due to Adverse Events compared with control (very low certainty).
1 finding from 1 review
- RR 2.84 [0.31, 26.08]5 studies · 180 participantsVery low
Muscle relaxant vs control
Total Number of Adverse Events ‐ only studies >24hrs duration · patients with pain management in rheumatoid arthritis
It is very uncertain whether muscle relaxant changes total Number of Adverse Events ‐ only studies >24hrs duration compared with control (very low certainty).
1 finding from 1 review
- RR 4.03 [1.08, 15.1]2 studies · 74 participantsVery low
Muscle relaxant vs control
Total Number of Adverse Events ‐ single dose studies · patients with pain management in rheumatoid arthritis
It is very uncertain whether muscle relaxant changes total Number of Adverse Events ‐ single dose studies compared with control (very low certainty).
1 finding from 1 review
- RR 1.4 [0.58, 3.41]3 studies · 106 participantsVery low
Muscle relaxant vs control
CNS adverse events · patients with pain management in rheumatoid arthritis
It is very uncertain whether muscle relaxant changes CNS adverse events compared with control (very low certainty).
1 finding from 1 review
- RR 5.96 [1.77, 20.08]2 studies · 74 participantsVery low
Oral cyclobenzaprine (muscle relaxant) vs placebo
Jaw pain (VAS) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral cyclobenzaprine (muscle relaxant) showed no clear difference in jaw pain (VAS) compared with placebo; GRADE not reported.
1 finding from 1 review
- Pharmacological interventions for pain in patients with temporomandibular disorders 2010 · Cochrane All outcomes3 weeksMD -1.30 [-2.67, 0.07]1 study · 41 participantsGRADE not reported
Oral cyclobenzaprine (muscle relaxant) vs placebo
Adverse events (reported; mild, no withdrawals) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
1 finding from 1 review
- Pharmacological interventions for pain in patients with temporomandibular disorders 2010 · Cochrane All outcomes3 weeksHerman et al 2002 (cyclobenzaprine) reported adverse effects. Per the review's Adverse effects of interventions section: 'All but one study (Lobo et al 2004) reported adverse effects. Most of the reported adverse…1 study · 41 participantsGRADE not reported