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Evidence found and GRADE certainty

120 questions · 126 findings · 18 reviews

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No studies found 20 · 15.9%GRADE not reported 8 · 6.3%Very low 28 · 22.2%Low 27 · 21.4%Moderate 27 · 21.4%High 16 · 12.7%

Home (point‐of‐use) fortification of foods with multiple micronutrient powders vs an iron‐only supplement

Anaemia · children aged 6 to 23 months

Home (point‐of‐use) fortification of foods with multiple… showed no clear difference in anaemia (haemoglobin values lower than 110 g/L) compared with an iron‐only supplement (low certainty).

1 finding from 1 review

Are disease‐modifying drugs for a first attack suggestive of multiple sclerosis (MS) effective and safe vs placebo?

Disability worsening

It is very uncertain whether are disease‐modifying drugs for a first attack suggestive of… changes disability‐worsening Proportion of participants with… compared with placebo? (very low certainty).

1 finding from 1 review

Are disease‐modifying drugs for a first attack suggestive of multiple sclerosis (MS) effective and safe vs placebo?

Relapse

It is very uncertain whether are disease‐modifying drugs for a first attack suggestive of… changes relapse Proportion of participants with relapse during 24 months of… compared with placebo? (very low certainty).

1 finding from 1 review

Are disease‐modifying drugs for a first attack suggestive of multiple sclerosis (MS) effective and safe vs placebo?

Adverse effects: at least one serious adverse event

Are disease‐modifying drugs for a first attack suggestive of… showed no clear difference in occurrence of at least one serious adverse event Proportion of… compared with placebo? (low certainty).

1 finding from 1 review

Are disease‐modifying drugs for a first attack suggestive of multiple sclerosis (MS) effective and safe vs placebo?

Discontinuation of medication due to adverse events

It is very uncertain whether are disease‐modifying drugs for a first attack suggestive of… changes withdrawls or drug discontinuation due to adverse events during 24… compared with placebo? (very low certainty).

1 finding from 1 review

Multiple doses of deworming drugs vs placebo

Death (between ages 1 and 6 years) · public health programmes to regularly treat all children aged 16 years or less

Multiple doses of deworming drugs showed no clear difference in mortality (between ages 1 and 6 years) compared with placebo (low certainty).

1 finding from 1 review