Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

38 questions · 40 findings · 7 reviews

No studies found 5 · 12.5%GRADE not reported 0 · 0%Very low 20 · 50%Low 11 · 27.5%Moderate 4 · 10%High 0 · 0%

Multi‐component intervention vs no intervention

Proportion of participants with low back pain/discomfort · sedentary workers with musculoskeletal symptoms

Multi‐component intervention showed no clear difference in proportion of participants with low back pain/discomfort compared with no intervention (low certainty).

1 finding from 1 review

Multi‐component intervention vs no intervention

Proportion of participants with upper back pain/discomfort · sedentary workers with musculoskeletal symptoms

Multi‐component intervention showed no clear difference in proportion of participants with upper back pain/discomfort compared with no intervention (low certainty).

1 finding from 1 review

Multi‐component intervention vs no intervention

Proportion of participants with neck pain/discomfort · sedentary workers with musculoskeletal symptoms

Multi‐component intervention showed no clear difference in proportion of participants with neck pain/discomfort compared with no intervention (low certainty).

1 finding from 1 review

Multi‐component intervention vs no intervention

Proportion of participants with shoulder pain/discomfort · sedentary workers with musculoskeletal symptoms

It is very uncertain whether multi‐component intervention changes proportion of participants with shoulder pain/discomfort compared with no intervention (very low certainty).

1 finding from 1 review

Multi‐component interventions (with telehealth as a component of care) vs usual care

Number of people experiencing at least 1 exacerbation/moderate to severe exacerbation · patients with chronic obstructive pulmonary disease

It is very uncertain whether multi‐component interventions (with telehealth as a component of care) changes number of people experiencing at least 1 exacerbation/moderate to… compared with usual care (very low certainty).

1 finding from 1 review

Multi‐component interventions (with telehealth as a component of care) vs usual care

Time to first exacerbation · patients with chronic obstructive pulmonary disease

It is very uncertain whether multi‐component interventions (with telehealth as a component of care) changes time to first exacerbation compared with usual care (very low certainty).

1 finding from 1 review

Multi‐component interventions (with telehealth as a component of care) vs usual care

QoL · patients with chronic obstructive pulmonary disease
3 findings from 1 review

Multi‐component interventions (with telehealth as a component of care) vs usual care

Transmission‐related outcomes: hospitalization ‐ Number or proportion of hospital admissions · patients with chronic obstructive pulmonary disease

Multi‐component interventions (with telehealth as a component of care) showed no clear difference in number of people who had at least 1 hospital admission compared with usual care (low certainty).

1 finding from 1 review

Multi‐component interventions (with telehealth as a component of care) vs usual care

Number of people re‐admitted (all‐cause) · patients with chronic obstructive pulmonary disease

Multi‐component interventions (with telehealth as a component of care) probably leads to lower number of people re‐admitted (all‐cause) compared with usual care (moderate certainty).

1 finding from 1 review

Multi‐component interventions (with telehealth as a component of care) vs usual care

Anti‐cytokine, all‐cause mortality ‐ uncertain risk of bias · patients with chronic obstructive pulmonary disease

It is very uncertain whether multi‐component interventions (with telehealth as a component of care) changes mortality (all‐cause) overall analysis compared with usual care (very low certainty).

1 finding from 1 review

Multi‐component interventions (with telehealth as a component of care) vs usual care

Adverse events: number of people with 1 or more (all‐cause) · patients with chronic obstructive pulmonary disease

It is very uncertain whether multi‐component interventions (with telehealth as a component of care) changes adverse events: number of people with 1 or more (all‐cause) compared with usual care (very low certainty).

1 finding from 1 review

Multi‐component intervention vs other treatments/routine care

Number experiencing adverse effects · the management of chronic obstructive pulmonary disease

It is very uncertain whether multi‐component intervention changes adverse events: number of people experiencing an AE compared with other intervention or routine, usual care or control treatment (very low certainty).

1 finding from 1 review

Multi‐component intervention vs other treatments/routine care

Number of participants experiencing any serious adverse events · the management of chronic obstructive pulmonary disease

Multi‐component intervention showed no clear difference in adverse events: number of people experiencing a serious adverse event compared with other intervention or routine, usual care or control treatment (low certainty).

1 finding from 1 review