Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

103 questions · 103 findings · 7 reviews · Pregnancy and Childbirth

No studies found 9 · 8.7%GRADE not reported 8 · 7.8%Very low 39 · 37.9%Low 39 · 37.9%Moderate 8 · 7.8%High 0 · 0%

Oral misoprostol vs vaginal misoprostol

Uterine hyperstimulation with fetal heart rate changes · women in the third trimester for induction of labour.

Oral misoprostol may leads to lower uterine hyperstimulation with fetal heart rate changes compared with vaginal misoprostol (low certainty).

1 finding from 1 review

Oral misoprostol vs vaginal misoprostol

Uterine hyperstimulation without fetal heart rate changes · women in the third trimester for induction of labour.

Oral misoprostol may leads to lower uterine hyperstimulation without fetal heart rate changes compared with vaginal misoprostol (low certainty).

1 finding from 1 review

Oral misoprostol vs vaginal misoprostol

Admission to neonatal intensive care unit · women in the third trimester for induction of labour.

Oral misoprostol showed no clear difference in admission to neonatal intensive care unit compared with vaginal misoprostol (moderate certainty).

1 finding from 1 review

Misoprostol vs surgery

Unplanned surgical intervention · incomplete miscarriage

Misoprostol may leads to higher unplanned surgical intervention compared with surgery (low certainty).

1 finding from 1 review

Misoprostol vs surgery

Women's views/acceptability of method · incomplete miscarriage

Misoprostol showed no clear difference in women's views/acceptability of method compared with surgery (moderate certainty).

1 finding from 1 review

Misoprostol vs surgery

Complete miscarriage · incomplete miscarriage

It is very uncertain whether misoprostol changes complete miscarriage compared with surgery (very low certainty).

1 finding from 1 review