Oral misoprostol vs vaginal misoprostol
Oral misoprostol may leads to lower vaginal birth within 24 hours compared with vaginal misoprostol (low certainty).
- RR 0.81 [0.68, 0.95]16 studies · 3451 participantsLow
Oral misoprostol may leads to lower vaginal birth within 24 hours compared with vaginal misoprostol (low certainty).
Oral misoprostol showed no clear difference in caesarean section compared with vaginal misoprostol (low certainty).
Oral misoprostol may leads to lower uterine hyperstimulation with fetal heart rate changes compared with vaginal misoprostol (low certainty).
Oral misoprostol may leads to higher oxytocin augmentation compared with vaginal misoprostol (low certainty).
Oral misoprostol may leads to lower uterine hyperstimulation without fetal heart rate changes compared with vaginal misoprostol (low certainty).
Oral misoprostol showed no clear difference in apgar score less than seven at five minutes compared with vaginal misoprostol (low certainty).
Oral misoprostol showed no clear difference in admission to neonatal intensive care unit compared with vaginal misoprostol (moderate certainty).
It is very uncertain whether misoprostol changes complete miscarriage compared with expectant care (very low certainty).
Misoprostol may leads to higher unplanned surgical intervention compared with surgery (low certainty).
Misoprostol showed no clear difference in women's views/acceptability of method compared with surgery (moderate certainty).
Misoprostol may leads to higher nausea compared with surgery (low certainty).
Misoprostol probably leads to higher vomiting compared with surgery (moderate certainty).
Misoprostol probably leads to higher diarrhoea compared with surgery (moderate certainty).
Misoprostol showed no clear difference in surgical evacuation compared with expectant care (low certainty).
Misoprostol showed no clear difference in unplanned surgical intervention compared with expectant care (low certainty).
It is very uncertain whether misoprostol changes complete miscarriage compared with surgery (very low certainty).