Vaginal misoprostol vs placebo
Pelvic infection · early fetal death (less than 24 weeks)
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Findings
What do systematic reviews say?
28 questions · 28 findings · 2 reviews
No studies found 1 · 3.6%GRADE not reported 4 · 14.3%Very low 5 · 17.9%Low 15 · 53.6%Moderate 3 · 10.7%High 0 · 0%
Vaginal misoprostol vs placebo
Nausea · early fetal death (less than 24 weeks)
Vaginal misoprostol showed no clear difference in nausea compared with placebo (low certainty).
1 finding from 1 review
- RR 1.38 [0.43, 4.4]2 studies · 88 participantsLow
Vaginal misoprostol vs placebo
Diarrhoea · early fetal death (less than 24 weeks)
Vaginal misoprostol showed no clear difference in diarrhoea compared with placebo (low certainty).
1 finding from 1 review
- RR 2.21 [0.35, 14.06]2 studies · 88 participantsLow
Vaginal misoprostol vs placebo
Blood loss: haemoglobin difference > 10 g/L · early fetal death (less than 24 weeks)
It is very uncertain whether vaginal misoprostol changes blood loss: haemoglobin difference > 10 g/L compared with placebo (very low certainty).
1 finding from 1 review
- RR 1.25 [0.38, 4.12]1 study · 50 participantsVery low
Vaginal misoprostol vs placebo
Opiate use (as a proxy measure for pain) for all participants on ITT (including those without confirmed AMI) · early fetal death (less than 24 weeks)
It is very uncertain whether vaginal misoprostol changes pain (opiate use) compared with placebo (very low certainty).
1 finding from 1 review
- RR 5 [0.25, 101.11]1 study · 84 participantsVery low
Vaginal misoprostol vs placebo
Woman’s satisfaction/acceptability of method · early fetal death (less than 24 weeks)
Vaginal misoprostol showed no clear difference in woman’s satisfaction/acceptability of method compared with placebo (low certainty).
1 finding from 1 review
- RR 1.17 [0.83, 1.64]1 study · 32 participantsLow
Vaginal misoprostol vs surgical evacuation of uterus
Complete miscarriage · early fetal death (less than 24 weeks)
Vaginal misoprostol may leads to lower complete miscarriage compared with surgical evacuation of uterus (low certainty).
1 finding from 1 review
- RR 0.4 [0.32, 0.5]6 studies · 943 participantsLow
Vaginal misoprostol vs surgical evacuation of uterus
Pelvic infection · early fetal death (less than 24 weeks)
Vaginal misoprostol showed no clear difference in pelvic infection compared with surgical evacuation of uterus (low certainty).
1 finding from 1 review
- RR 0.73 [0.39, 1.37]1 study · 618 participantsLow