Findings

What do systematic reviews say?

22 questions · 44 findings · 1 reviews

No studies found 4 · 9.1%GRADE not reported 30 · 68.2%Very low 10 · 22.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Antimicrobial resistance · Adults with periodontitis (chronic and aggressive)

The review found no eligible studies for this question.

1 finding from 1 review

Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
Long-term (≥ 1 year)
Included studies have not reported this outcome
Studies not reported
No studies found

Adverse events · Adults with periodontitis (chronic and aggressive)

It is very uncertain whether amoxicillin + metronidazole + SRP changes adverse events compared with SRP (very low certainty).

1 finding from 1 review

Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
Long-term (≥ 1 year)
Most common adverse events were mild gastrointestinal disturbances, nausea and vomiting, metallic taste, and diarrhoea in the intervention group. Control group reported adverse events like hypothermia, mild…
2 studies · 389 participants
Very low