Evidence Gaps

What do systematic reviews say?

1 questions · 3 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 2 · 66.7%Very low 1 · 33.3%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Percentage of closed pockets · Adults with periodontitis (chronic and aggressive)

Amoxicillin + metronidazole + SRP led to lower percentage of closed pockets compared with SRP; GRADE not reported.

3 findings from 1 review

Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
Intermediate-term (> 3 months to < 1 year)
MD -13.90 [-24.16, -3.64]
1 study · 44 participants
GRADE not reported
Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
Long-term (≥ 1 year)
MD -16.20 [-25.87, -6.53]
1 study · 44 participants
Very low
Adjunctive systemic antimicrobials for the non‐surgical treatment of periodontitis 2020 · Cochrane All outcomes
Short-term (≤ 3 months)
MD -10.05 [-18.78, -1.32]
2 studies · 73 participants
GRADE not reported