Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Neuromuscular

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 66.7%Moderate 1 · 33.3%High 0 · 0%

Methotrexate vs placebo

Participants able to reduce corticosteroid or IVIg dose by more than 20% · people with CIDP

Methotrexate showed no clear difference in participants able to reduce corticosteroid or IVIg dose by more than… compared with placebo (moderate certainty).

1 finding from 1 review

Immunomodulatory treatment other than corticosteroids, immunoglobulin and plasma exchange for chronic inflammatory… 2017 · Cochrane Headline outcomes only
RR 1.21 [0.4, 3.7]
1 study · 59 participants
Moderate

Methotrexate vs placebo

Change in disability after 26 or more weeks Overall Neuropathy Limitation Scale. Scale from: 0 to 12. · people with CIDP

1 finding from 1 review

Immunomodulatory treatment other than corticosteroids, immunoglobulin and plasma exchange for chronic inflammatory… 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Low

Methotrexate vs placebo

Change in disability after 26 or more weeks Amsterdam Linear Disability Scale. Scale from: 0 to 100. · people with CIDP

1 finding from 1 review

Immunomodulatory treatment other than corticosteroids, immunoglobulin and plasma exchange for chronic inflammatory… 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Low