What do systematic reviews say?

Medication reconciliation interventions vs no medication reconciliation

Medication reconciliation showed no clear difference in medication errors ( compared with no medication reconciliation (low certainty).

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  OR 0.55 [0.17, 1.74]
  3 studies · 379 participants
  Low

Medication reconciliation: 1 or 2 vs 4 charts open simultaneously

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  no estimate extracted
  11504 participants
  Very low

Medication reconciliation: pharmacist vs other professionals

Medication reconciliation: pharmacist may leads to lower medication errors ( compared with other professionals (low certainty).

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  OR 0.21 [0.09, 0.48]
  8 studies · 2648 participants
  Low

Medication reconciliation interventions vs usual care

It is very uncertain whether medication reconciliation interventions changes ≥ 1 medication discrepancy per participant (dichotomous) compared with standard care (very low certainty).

• Impact of medication reconciliation for improving transitions of care 2018 · Cochrane Headline outcomes only
  RR 0.53 [0.42, 0.67]
  20 studies · 4629 participants
  Very low

Medication reconciliation interventions vs usual care

• Impact of medication reconciliation for improving transitions of care 2018 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 1963 participants
  Very low
• Impact of medication reconciliation for improving transitions of care 2018 · Cochrane Headline outcomes only
  RR 0.13 [0.01, 1.29]
  2 studies · 3595 participants
  Very low

Medication reconciliation interventions vs no medication reconciliation

Medication reconciliation probably leads to lower ADEs ( compared with no medication reconciliation (moderate certainty).

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  OR 0.38 [0.18, 0.8]
  3 studies · 1336 participants
  Moderate

Medication reconciliation interventions vs no medication reconciliation

It is very uncertain whether medication reconciliation changes mortality during hospitalisation ( compared with no medication reconciliation (very low certainty).

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  RR 3.85 [0.44, 33.89]
  1 study · 212 participants
  Very low

Medication reconciliation interventions vs no medication reconciliation

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 527 participants
  Low

Medication reconciliation interventions vs no medication reconciliation

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 131 participants
  Low

Medication reconciliation interventions vs no medication reconciliation

Medication reconciliation probably leads to higher discrepancy resolution ( compared with no medication reconciliation (moderate certainty).

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  RR 7.48 [5.62, 9.95]
  1 study · 564 participants
  Moderate

Medication reconciliation: multimodal intervention vs usual care

It is very uncertain whether medication reconciliation: multimodal intervention changes medication error ( compared with usual care (very low certainty).

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  RR 0.92 [0.87, 0.97]
  1648 participants
  Very low

Medication reconciliation by trained pharmacist technician vs pharmacist

It is very uncertain whether medication reconciliation by trained pharmacist technician changes medication errors ( compared with pharmacist (very low certainty).

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  OR 0.65 [0.25, 1.7]
  2 studies · 306 participants
  Very low

Medication reconciliation: before vs at admission

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 307 participants
  Low

Medication reconciliation: pharmacist vs other professionals

Medication reconciliation: pharmacist showed no clear difference in readmission at 1 month ( compared with other professionals (moderate certainty).

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  RR 0.93 [0.76, 1.14]
  2 studies · 997 participants
  Moderate

Medication reconciliation: pharmacist vs other professionals

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 3983 participants
  Low

Medication reconciliation: pharmacist vs other professionals

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 724 participants
  Low

Medication reconciliation: pharmacist vs other professionals

Medication reconciliation: pharmacist may leads to higher discrepancy resolution ( compared with other professionals (low certainty).

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  OR 4.8 [1.81, 12.76]
  3 studies · 1449 participants
  Low

Medication reconciliation: pharmacist vs other professionals

Medication reconciliation: pharmacist showed no clear difference in ADEs ( compared with other professionals (low certainty).

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  OR 1.34 [0.73, 2.44]
  3 studies · 2873 participants
  Low

Medication reconciliation: pharmacist vs other professionals

Medication reconciliation: pharmacist showed no clear difference in mortality during hospitalisation ( compared with other professionals (moderate certainty).

• Reducing medication errors for adults in hospital settings 2021 · Cochrane Headline outcomes only
  RR 0.99 [0.57, 1.73]
  2 studies · 1000 participants
  Moderate

Medication reconciliation interventions vs usual care

It is very uncertain whether medication reconciliation interventions changes PADEs compared with standard care (very low certainty).

• Impact of medication reconciliation for improving transitions of care 2018 · Cochrane Headline outcomes only
  RR 0.37 [0.09, 1.57]
  3 studies · 1253 participants
  Very low