Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews · Infectious Diseases

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 4 · 80%Low 1 · 20%Moderate 0 · 0%High 0 · 0%

Serious adverse events · adults and adolescents with scrub typhus

1 finding from 1 review

Antibiotics for treating scrub typhus 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 242 participants
Very low

Treatment failure · adults and adolescents with scrub typhus

It is very uncertain whether macrolides changes treatment failure compared with doxycycline (very low certainty).

1 finding from 1 review

Antibiotics for treating scrub typhus 2018 · Cochrane Headline outcomes only
RR 2.71 [0.12, 63.84]
3 studies · 242 participants
Very low

Resolution of fever within 48 hours · adults and adolescents with scrub typhus

It is very uncertain whether macrolides changes resolution of fever within 48 hours compared with doxycycline (very low certainty).

1 finding from 1 review

Antibiotics for treating scrub typhus 2018 · Cochrane Headline outcomes only
RR 0.81 [0.32, 2.03]
2 studies · 150 participants
Very low

Resolution of fever within 5 days · adults and adolescents with scrub typhus

Macrolides showed no clear difference in resolution of fever within 5 days compared with doxycycline (low certainty).

1 finding from 1 review

Antibiotics for treating scrub typhus 2018 · Cochrane Headline outcomes only
RR 1.05 [0.99, 1.1]
2 studies · 185 participants
Low

Time to defervescence · adults and adolescents with scrub typhus

1 finding from 1 review

Antibiotics for treating scrub typhus 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 242 participants
Very low