Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 20%Low 2 · 40%Moderate 2 · 40%High 0 · 0%

Lower blood pressure targets vs standard blood pressure targets

Total mortality · cardiovascular disease with high blood pressure

Lower blood pressure targets showed no clear difference in total mortality compared with standard blood pressure targets (moderate certainty).

1 finding from 1 review

Blood pressure targets for the treatment of people with hypertension and cardiovascular disease 2022 · Cochrane Headline outcomes only
RR 1.05 [0.91, 1.23]
7 studies · 9595 participants
Moderate

Lower blood pressure targets vs standard blood pressure targets

Total serious adverse events · cardiovascular disease with high blood pressure

Lower blood pressure targets showed no clear difference in total serious adverse events compared with standard blood pressure targets (low certainty).

1 finding from 1 review

Blood pressure targets for the treatment of people with hypertension and cardiovascular disease 2022 · Cochrane Headline outcomes only
RR 1.01 [0.94, 1.08]
7 studies · 9595 participants
Low

Lower blood pressure targets vs standard blood pressure targets

Cardiovascular events · cardiovascular disease with high blood pressure

Lower blood pressure targets showed no clear difference in total cardiovascular events compared with standard blood pressure targets (low certainty).

1 finding from 1 review

Blood pressure targets for the treatment of people with hypertension and cardiovascular disease 2022 · Cochrane Headline outcomes only
RR 0.89 [0.8, 1]
7 studies · 9595 participants
Low

Lower blood pressure targets vs standard blood pressure targets

Cardiovascular mortality · cardiovascular disease with high blood pressure

Lower blood pressure targets showed no clear difference in cardiovascular mortality compared with standard blood pressure targets (moderate certainty).

1 finding from 1 review

Blood pressure targets for the treatment of people with hypertension and cardiovascular disease 2022 · Cochrane Headline outcomes only
RR 1.03 [0.82, 1.29]
6 studies · 9484 participants
Moderate

Lower blood pressure targets vs standard blood pressure targets

Withdrawals due to adverse events · cardiovascular disease with high blood pressure

It is very uncertain whether lower blood pressure targets changes participant withdrawals due to adverse effects compared with standard blood pressure targets (very low certainty).

1 finding from 1 review

Blood pressure targets for the treatment of people with hypertension and cardiovascular disease 2022 · Cochrane Headline outcomes only
RR 8.16 [2.06, 32.28]
3 studies · 801 participants
Very low