Low protein diet vs normal protein diet
Change in 24‐hour urinary protein excretion · adults with DKD
1 finding from 1 review
- no estimate extracted1 study · 80 participantsVery low
Findings
What do systematic reviews say?
11 questions · 11 findings · 2 reviews
No studies found 0 · 0%GRADE not reported 1 · 9.1%Very low 3 · 27.3%Low 4 · 36.4%Moderate 3 · 27.3%High 0 · 0%
Very low protein diet vs low or normal protein diet
Death (all causes) · non‐diabetic adults with CKD
Very low protein diet showed no clear difference in death (all causes) compared with low or normal protein diet (moderate certainty).
1 finding from 1 review
- Low protein diets for non‐diabetic adults with chronic kidney disease 2020 · Cochrane Headline outcomes onlyRR 1.26 [0.62, 2.54]6 studies · 681 participantsModerate
Very low protein diet vs low or normal protein diet
ESKD · non‐diabetic adults with CKD
Very low protein diet probably leads to lower ESKD compared with low or normal protein diet (moderate certainty).
1 finding from 1 review
- Low protein diets for non‐diabetic adults with chronic kidney disease 2020 · Cochrane Headline outcomes onlyRR 0.64 [0.49, 0.85]10 studies · 1010 participantsModerate
Very low protein diet vs low or normal protein diet
End or change in GFR · non‐diabetic adults with CKD
1 finding from 1 review
- Low protein diets for non‐diabetic adults with chronic kidney disease 2020 · Cochrane Headline outcomes onlyno estimate extracted6 studies · 456 participantsLow
Low protein diet vs normal protein diet
Death (all causes) · non‐diabetic adults with CKD
Low protein diet showed no clear difference in death (all causes) compared with normal protein diet (moderate certainty).
1 finding from 1 review
- Low protein diets for non‐diabetic adults with chronic kidney disease 2020 · Cochrane Headline outcomes onlyRR 0.77 [0.51, 1.18]5 studies · 1680 participantsModerate
Low protein diet vs normal protein diet
ESKD · non‐diabetic adults with CKD
Low protein diet showed no clear difference in ESKD compared with normal protein diet (low certainty).
1 finding from 1 review
- Low protein diets for non‐diabetic adults with chronic kidney disease 2020 · Cochrane Headline outcomes onlyRR 1.05 [0.73, 1.53]6 studies · 1814 participantsLow
Low protein diet vs normal protein diet
End or change in GFR · non‐diabetic adults with CKD
1 finding from 1 review
- Low protein diets for non‐diabetic adults with chronic kidney disease 2020 · Cochrane Headline outcomes onlyno estimate extracted8 studies · 1680 participantsVery low
Low protein diet vs normal protein diet
Death (any cause) · adults with DKD
Low protein diet showed no clear difference in death (any cause) compared with usual or unrestricted protein diet (low certainty).
1 finding from 1 review
- RR 0.38 [0.1, 1.44]5 studies · 358 participantsLow
Low protein diet vs normal protein diet
Kidney failure · adults with DKD
Low protein diet showed no clear difference in kidney failure compared with usual or unrestricted protein diet (low certainty).
1 finding from 1 review
- RR 1.16 [0.38, 3.59]4 studies · 287 participantsLow
Low protein diet vs normal protein diet
Change in GFR · adults with DKD
1 finding from 1 review
- no estimate extracted7 studies · 367 participantsVery low
Low protein diet vs normal protein diet
Malnutrition · adults with DKD
1 finding from 1 review
- no estimate extracted7 studies · 471 participantsGRADE not reported