Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

360 questions · 397 findings · 57 reviews

No studies found 74 · 18.6%GRADE not reported 83 · 20.9%Very low 66 · 16.6%Low 88 · 22.2%Moderate 62 · 15.6%High 24 · 6%

Low‐GI dietary advice vs moderate‐ to high‐GI dietary advice (child outcomes)

Large‐for‐gestational age · pregnant women

It is very uncertain whether low‐GI dietary advice changes large‐for‐gestational age compared with moderate‐ to high‐GI dietary advice (child outcomes) (very low certainty).

1 finding from 1 review

Lower unemployment rate vs Higher unemployment rate (low <=5% / medium >5-10% / high >10%)

Caries experience (mean DMFT) · 12-year-old children across European countries (national/regional epidemiological surveys, 2011-2022)

Mean DMFT tended to increase with unemployment rate (low 1.23, medium 2.08, high 2.38; ANOVA p<.05); descriptive country-level means only, not meta-analyzed or GRADE-rated.

3 findings from 1 review

Low‐dose opioid based general anaesthesia vs high‐dose opioid based general anaesthesia

Mortality ‐ Death at any time after surgery · adult cardiac surgical patients

Low‐dose opioid‐based GA showed no clear difference in mortality ‐ Death at any time after surgery compared with high‐dose opioid‐based GA (low certainty).

1 finding from 1 review

Low‐dose opioid based general anaesthesia vs high‐dose opioid based general anaesthesia

Postoperative complications ‐ Myocardial infarction · adult cardiac surgical patients

Low‐dose opioid‐based GA showed no clear difference in postoperative myocardial infarction compared with high‐dose opioid‐based GA (low certainty).

1 finding from 1 review

Lower‐dose methylnaltrexone vs higher dose

Laxation response: risk of spontaneous rescue‐free bowel movements in the short terma · people receiving palliative care irrespective of whether they had cancer with opioid‐induced bowel dysfunction

Methylnaltrexone lower dose showed no clear difference in laxation response: risk of spontaneous rescue‐free bowel… compared with higher dose (low certainty).

1 finding from 1 review

Lower‐dose methylnaltrexone vs higher dose

Laxation response: risk of spontaneous rescue‐free bowel movements in the medium termb · people receiving palliative care irrespective of whether they had cancer with opioid‐induced bowel dysfunction

It is very uncertain whether methylnaltrexone lower dose changes laxation response: risk of spontaneous rescue‐free bowel… compared with higher dose (very low certainty).

1 finding from 1 review

Lower‐dose methylnaltrexone vs higher dose

Laxation response: patient assessment of change in bowel status at the end of trial · people receiving palliative care irrespective of whether they had cancer with opioid‐induced bowel dysfunction

Methylnaltrexone lower dose showed no clear difference in laxation response: patient assessment of change in bowel statusgat… compared with higher dose (low certainty).

1 finding from 1 review

Lower‐dose methylnaltrexone vs higher dose

Symptoms of opioid withdrawal in the medium term · people receiving palliative care irrespective of whether they had cancer with opioid‐induced bowel dysfunction

Methylnaltrexone lower dose showed no clear difference in symptoms of opioid withdrawal in the medium term compared with higher dose (low certainty).

1 finding from 1 review