Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Headline outcomes only

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 57.1%Moderate 3 · 42.9%High 0 · 0%

Any stroke within 30 days of operation (primary outcome) · patients with symptomatic or asymptomatic carotid disease

1 finding from 1 review

Local versus general anaesthesia for carotid endarterectomy 2021 · Cochrane Headline outcomes only
0.91 [0.66, 1.26]
13 studies · 4663 participants
Moderate

Death within 30 days of operation · patients with symptomatic or asymptomatic carotid disease

Local anaesthesia showed no clear difference in death within 30 days of operation compared with general anaesthesia (low certainty).

1 finding from 1 review

Local versus general anaesthesia for carotid endarterectomy 2021 · Cochrane Headline outcomes only
OR 0.61 [0.35, 1.06]
12 studies · 4421 participants
Low

Perioperative ipsilateral stroke (< 30 days) · patients with symptomatic or asymptomatic carotid disease

Local anaesthesia showed no clear difference in ipsilateral stroke within 30 days of operation compared with general anaesthesia (low certainty).

1 finding from 1 review

Local versus general anaesthesia for carotid endarterectomy 2021 · Cochrane Headline outcomes only
OR 1.03 [0.71, 1.48]
2 studies · 3733 participants
Low

Perioperative death and strokes · patients with symptomatic or asymptomatic carotid disease

Local anaesthesia showed no clear difference in stroke or death within 30 days of operation compared with general anaesthesia (moderate certainty).

1 finding from 1 review

Local versus general anaesthesia for carotid endarterectomy 2021 · Cochrane Headline outcomes only
OR 0.85 [0.62, 1.16]
11 studies · 4391 participants
Moderate

Myocardial infarction (0 to 30 days) · patients with symptomatic or asymptomatic carotid disease

Local anaesthesia showed no clear difference in myocardial infarction within 30 days of operation compared with general anaesthesia (low certainty).

1 finding from 1 review

Local versus general anaesthesia for carotid endarterectomy 2021 · Cochrane Headline outcomes only
OR 1.53 [0.67, 3.47]
12 studies · 4567 participants
Low

Local haemorrhage · patients with symptomatic or asymptomatic carotid disease

Local anaesthesia showed no clear difference in local haemorrhage compared with general anaesthesia (moderate certainty).

1 finding from 1 review

Local versus general anaesthesia for carotid endarterectomy 2021 · Cochrane Headline outcomes only
OR 0.99 [0.79, 1.25]
6 studies · 4186 participants
Moderate

Arteries shunted · patients with symptomatic or asymptomatic carotid disease

Local anaesthesia may leads to lower arteries shunted compared with general anaesthesia (low certainty).

1 finding from 1 review

Local versus general anaesthesia for carotid endarterectomy 2021 · Cochrane Headline outcomes only
OR 0.25 [0.22, 0.29]
8 studies · 4133 participants
Low