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Evidence found and GRADE certainty

1 questions · 1 findings · 1 reviews

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Lithium vs valproate

Efficacy: response (categorical) YMRS/SADS‐C decrease ≥ 50% by end of study · acute mania

Lithium showed no clear difference in efficacy: response (categorical) YMRS/SADS‐C decrease ≥ 50% by end… compared with valproate (moderate certainty).

1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    OR 1.22 [0.87, 1.7]
    5 studies · 607 participants
    Moderate