Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1 questions · 1 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 100%High 0 · 0%

Lithium vs valproate

Nausea · acute mania

Lithium showed no clear difference in adverse event: nausea compared with valproate (moderate certainty).

1 finding from 1 review
  • Lithium for acute mania 2019 · Cochrane Headline outcomes only
    OR 1.53 [0.97, 2.4]
    4 studies · 583 participants
    Moderate