Findings

What do systematic reviews say?

24 questions · 24 findings · 3 reviews

No studies found 9 · 37.5%GRADE not reported 0 · 0%Very low 3 · 12.5%Low 3 · 12.5%Moderate 1 · 4.2%High 8 · 33.3%

Withdrawals due to adverse events · patients with rheumatoid arthritis in adults

1 finding from 1 review

Leflunomide for the treatment of rheumatoid arthritis 2002 · Cochrane Headline outcomes only
no estimate extracted
1 study · 263 participants
Moderate

For outcome · patients with rheumatoid arthritis in adults

The review found no eligible studies for this question.

1 finding from 1 review

Leflunomide for the treatment of rheumatoid arthritis 2002 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

ACR 50% improvement · patients with rheumatoid arthritis in adults

Summary of findings: leflunomide + methotrexate leads to higher ACR 50 at 6 months compared with methotrexate, 6 months (high certainty).

1 finding from 1 review

Leflunomide for the treatment of rheumatoid arthritis 2002 · Cochrane Headline outcomes only
RR 4.35 [2.09, 9.03]
1 study · 263 participants
High

HAQ change from baseline Scale from: 0 to 3. · patients with rheumatoid arthritis in adults

1 finding from 1 review

Leflunomide for the treatment of rheumatoid arthritis 2002 · Cochrane Headline outcomes only
no estimate extracted
1 study · 263 participants
High