Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Headline outcomes only

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 7 · 100%Moderate 0 · 0%High 0 · 0%

Late parenteral nutrition vs early parenteral nutrition

In‐hospital all‐cause mortality · critically ill term and late preterm infants

Late parenteral nutrition may leads to lower in‐hospital all‐cause mortality compared with early parenteral nutrition (low certainty).

1 finding from 1 review

Early versus late parenteral nutrition for critically ill term and late preterm infants 2020 · Cochrane Headline outcomes only
RR 0.35 [0.14, 0.87]
1 study · 209 participants
Low

Late parenteral nutrition vs early parenteral nutrition

Neonatal mortality · critically ill term and late preterm infants

Late parenteral nutrition may leads to lower neonatal mortality (within 28 days of birth) compared with early parenteral nutrition (low certainty).

1 finding from 1 review

Early versus late parenteral nutrition for critically ill term and late preterm infants 2020 · Cochrane Headline outcomes only
RR 0.29 [0.1, 0.88]
1 study · 209 participants
Low

Late parenteral nutrition vs early parenteral nutrition

Healthcare‐associated blood stream infection · critically ill term and late preterm infants

Late parenteral nutrition showed no clear difference in healthcare‐associated blood stream infection compared with early parenteral nutrition (low certainty).

1 finding from 1 review

Early versus late parenteral nutrition for critically ill term and late preterm infants 2020 · Cochrane Headline outcomes only
RR 0.22 [0.05, 1.01]
1 study · 209 participants
Low

Late parenteral nutrition vs early parenteral nutrition

Healthcare‐associated infection (any type) · critically ill term and late preterm infants

Late parenteral nutrition may leads to lower healthcare‐associated infection (any type) compared with early parenteral nutrition (low certainty).

1 finding from 1 review

Early versus late parenteral nutrition for critically ill term and late preterm infants 2020 · Cochrane Headline outcomes only
RR 0.53 [0.32, 0.89]
1 study · 209 participants
Low

Late parenteral nutrition vs early parenteral nutrition

Length of hospital stay · critically ill term and late preterm infants

Late parenteral nutrition showed no clear difference in mean duration of hospital stay compared with early parenteral nutrition (low certainty).

1 finding from 1 review

Early versus late parenteral nutrition for critically ill term and late preterm infants 2020 · Cochrane Headline outcomes only
MD 9.5
1 study · 209 participants
Low

Late parenteral nutrition vs early parenteral nutrition

Duration of mechanical ventilation · critically ill term and late preterm infants

Late parenteral nutrition showed no clear difference in mean duration of mechanical ventilation compared with early parenteral nutrition (low certainty).

1 finding from 1 review

Early versus late parenteral nutrition for critically ill term and late preterm infants 2020 · Cochrane Headline outcomes only
MD 3.4
1 study · 209 participants
Low

Late parenteral nutrition vs early parenteral nutrition

Hypoglycaemia · critically ill term and late preterm infants

Late parenteral nutrition showed no clear difference in hypoglycaemia compared with early parenteral nutrition (low certainty).

1 finding from 1 review

Early versus late parenteral nutrition for critically ill term and late preterm infants 2020 · Cochrane Headline outcomes only
RR 1.64 [0.91, 2.96]
1 study · 209 participants
Low