What do systematic reviews say?

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical… showed no clear difference in proportion of eyes within ± 0.5 diopters of target refraction, 12… compared with LASIK with a femtosecond laser (low certainty).

• Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome compared to LASIK with a femtosecond… 2020 · Cochrane Headline outcomes only
  RR 0.97 [0.85, 1.11]
  1 study · 79 participants
  Low

Laser‐assisted in‐situ keratomileusis (LASIK) vs photorefractive keratectomy (PRK)

Laser‐assisted in‐situ keratomileusis (LASIK) showed no clear difference in within 0.50 D of target refraction compared with photorefractive keratectomy (PRK) (low certainty).

• Laser‐assisted in‐situ keratomileusis (LASIK) versus photorefractive keratectomy (PRK) for myopia 2013 · Cochrane Headline outcomes only
  OR 1.45 [0.99, 2.1]
  7 studies · 1007 participants
  Low

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

• Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome compared to LASIK with a femtosecond… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 42 participants
  Low

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

• Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome compared to LASIK with a femtosecond… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 168 participants
  Low

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

It is very uncertain whether laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical… changes corneal haze, any time point compared with LASIK with a femtosecond laser (very low certainty).

• Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome compared to LASIK with a femtosecond… 2020 · Cochrane Headline outcomes only
  RR 0.33 [0.01, 7.96]
  1 study · 86 participants
  Very low

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical… may leads to higher dry eye, any time point compared with LASIK with a femtosecond laser (low certainty).

• Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome compared to LASIK with a femtosecond… 2020 · Cochrane Headline outcomes only
  RR 5.74 [2.92, 11.29]
  1 study · 183 participants
  Low

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical… may leads to lower diffuse lamellar keratitis, any time point compared with LASIK with a femtosecond laser (low certainty).

• Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome compared to LASIK with a femtosecond… 2020 · Cochrane Headline outcomes only
  RR 0.27 [0.1, 0.78]
  3 studies · 134 participants
  Low

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

It is very uncertain whether laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical… changes epithelial ingrowth, any time point compared with LASIK with a femtosecond laser (very low certainty).

• Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome compared to LASIK with a femtosecond… 2020 · Cochrane Headline outcomes only
  RR 1.04 [0.11, 9.42]
  2 studies · 102 participants
  Very low