What do systematic reviews say?

Laparoscopic myomectomy vs myomectomy by laparotomy or mini‐laparotomy

It is very uncertain whether laparoscopic myomectomy changes live birth rate compared with myomectomy by laparotomy or mini‐laparotomy (very low certainty).

• Surgical treatment of fibroids for subfertility 2020 · Cochrane Headline outcomes only
  OR 0.8 [0.42, 1.5]
  2 studies · 177 participants
  Very low

Laparoscopic myomectomy vs myomectomy by laparotomy or mini‐laparotomy

It is very uncertain whether laparoscopic myomectomy changes preterm delivery rate compared with myomectomy by laparotomy or mini‐laparotomy (very low certainty).

• Surgical treatment of fibroids for subfertility 2020 · Cochrane Headline outcomes only
  OR 0.7 [0.11, 4.29]
  2 studies · 177 participants
  Very low

Laparoscopic myomectomy vs myomectomy by laparotomy or mini‐laparotomy

It is very uncertain whether laparoscopic myomectomy changes clinical pregnancy rate compared with myomectomy by laparotomy or mini‐laparotomy (very low certainty).

• Surgical treatment of fibroids for subfertility 2020 · Cochrane Headline outcomes only
  OR 0.96 [0.52, 1.78]
  2 studies · 177 participants
  Very low

Laparoscopic myomectomy vs myomectomy by laparotomy or mini‐laparotomy

It is very uncertain whether laparoscopic myomectomy changes ongoing pregnancy rate compared with myomectomy by laparotomy or mini‐laparotomy (very low certainty).

• Surgical treatment of fibroids for subfertility 2020 · Cochrane Headline outcomes only
  OR 1.61 [0.26, 10.04]
  1 study · 115 participants
  Very low

Laparoscopic myomectomy vs myomectomy by laparotomy or mini‐laparotomy

It is very uncertain whether laparoscopic myomectomy changes miscarriage Rate compared with myomectomy by laparotomy or mini‐laparotomy (very low certainty).

• Surgical treatment of fibroids for subfertility 2020 · Cochrane Headline outcomes only
  OR 1.25 [0.4, 3.89]
  2 studies · 177 participants
  Very low

Laparoscopic myomectomy vs myomectomy by laparotomy or mini‐laparotomy

It is very uncertain whether laparoscopic myomectomy changes caesarean section rate compared with myomectomy by laparotomy or mini‐laparotomy (very low certainty).

• Surgical treatment of fibroids for subfertility 2020 · Cochrane Headline outcomes only
  OR 0.69 [0.34, 1.39]
  2 studies · 177 participants
  Very low

Laparoscopic myomectomy vs open myomectomy (all types)

• Minimally invasive surgical techniques versus open myomectomy for uterine fibroids 2014 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 148 participants
  Moderate

Laparoscopic myomectomy vs open myomectomy (all types)

• Minimally invasive surgical techniques versus open myomectomy for uterine fibroids 2014 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 232 participants
  Moderate

Laparoscopic myomectomy vs open myomectomy (all types)

• Minimally invasive surgical techniques versus open myomectomy for uterine fibroids 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 80 participants
  Moderate

Laparoscopic myomectomy vs open myomectomy (all types)

Laparoscopic myomectomy showed no clear difference in perioperative in‐hospital adverse events; unscheduled return to… compared with open myomectomy (all types) (low certainty).

• Minimally invasive surgical techniques versus open myomectomy for uterine fibroids 2014 · Cochrane Headline outcomes only
  OR 3.04 [0.12, 75.86]
  2 studies · 188 participants
  Low

Laparoscopic myomectomy vs open myomectomy (all types)

Laparoscopic myomectomy showed no clear difference in perioperative in‐hospital adverse events; laparoconversion compared with open myomectomy (all types) (moderate certainty).

• Minimally invasive surgical techniques versus open myomectomy for uterine fibroids 2014 · Cochrane Headline outcomes only
  OR 1.11 [0.44, 2.83]
  8 studies · 756 participants
  Moderate

Laparoscopic myomectomy vs open myomectomy (all types)

Laparoscopic myomectomy showed no clear difference in perioperative in‐hospital adverse events; injury to pelvic organs compared with open myomectomy (all types) (moderate certainty).

• Minimally invasive surgical techniques versus open myomectomy for uterine fibroids 2014 · Cochrane Headline outcomes only
  OR 3.04 [0.12, 75.86]
  1 study · 148 participants
  Moderate

Laparoscopic myomectomy vs open myomectomy (all types)

Laparoscopic myomectomy probably leads to lower in‐hospital adverse events; postoperative fever compared with open myomectomy (all types) (moderate certainty).

• Minimally invasive surgical techniques versus open myomectomy for uterine fibroids 2014 · Cochrane Headline outcomes only
  OR 0.44 [0.26, 0.77]
  6 studies · 635 participants
  Moderate