Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Epilepsy

No studies found 2 · 28.6%GRADE not reported 0 · 0%Very low 5 · 71.4%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Seizure freedom · patients with AD and epileptic seizures

It is very uncertain whether lamotrigine changes proportion with seizure freedom compared with phenobarbital (very low certainty).

1 finding from 1 review

Treatment of epilepsy for people with Alzheimer's disease 2021 · Cochrane Headline outcomes only
RR 0.84 [0.35, 2.02]
1 study · 57 participants
Very low

Proportion with adverse events · patients with AD and epileptic seizures

It is very uncertain whether lamotrigine changes proportion with adverse events compared with phenobarbital (very low certainty).

1 finding from 1 review

Treatment of epilepsy for people with Alzheimer's disease 2021 · Cochrane Headline outcomes only
RR 0.68 [0.3, 1.53]
1 study · 57 participants
Very low

50% or greater reduction in seizure frequency · patients with AD and epileptic seizures

It is very uncertain whether lamotrigine changes reduction in seizure frequency of 50% or more compared with phenobarbital (very low certainty).

1 finding from 1 review

Treatment of epilepsy for people with Alzheimer's disease 2021 · Cochrane Headline outcomes only
RR 0.91 [0.6, 1.38]
1 study · 57 participants
Very low

Proportion with seizure freedom in dominantly inherited AD · patients with AD and epileptic seizures

The review found no eligible studies for this question.

1 finding from 1 review

Treatment of epilepsy for people with Alzheimer's disease 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Change in cognition · patients with AD and epileptic seizures

1 finding from 1 review

Treatment of epilepsy for people with Alzheimer's disease 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 57 participants
Very low

Change in neuropsychiatric symptoms · patients with AD and epileptic seizures

1 finding from 1 review

Treatment of epilepsy for people with Alzheimer's disease 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 57 participants
Very low

Improvement in quality of life · patients with AD and epileptic seizures

The review found no eligible studies for this question.

1 finding from 1 review

Treatment of epilepsy for people with Alzheimer's disease 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found