What do systematic reviews say?

Lactoferrin supplementation vs control

Lactoferrin supplementation showed no clear difference in chronic lung disease№ of participants: 2984(5 RCTs) compared with control (low certainty).

• Enteral lactoferrin supplementation for prevention of sepsis and necrotizing enterocolitis in preterm infants 2020 · Cochrane Headline outcomes only
  RR 1 [0.89, 1.12]
  Studies not reported
  Low