What do systematic reviews say?

LNG vs no treatment

The review found no eligible studies for this question.

• Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

LNG‐IUS vs hysterectomy

LNG‐IUS showed no clear difference in satisfaction compared with hysterectomy (low certainty).

• Progestogen‐releasing intrauterine systems for heavy menstrual bleeding 2020 · Cochrane Headline outcomes only
  RR 1.01 [0.94, 1.08]
  1 study · 232 participants
  Low

LNG‐IUS vs any other medical treatment

It is very uncertain whether LNG‐IUS changes satisfaction compared with any other medical treatment (very low certainty).

• Progestogen‐releasing intrauterine systems for heavy menstrual bleeding 2020 · Cochrane Headline outcomes only
  RR 1.28 [1.01, 1.63]
  3 studies · 141 participants
  Very low

LNG‐IUS vs endometrial ablation

LNG‐IUS showed no clear difference in satisfaction with treatment compared with endometrial ablation (low certainty).

• Progestogen‐releasing intrauterine systems for heavy menstrual bleeding 2020 · Cochrane Headline outcomes only
  RR 0.95 [0.85, 1.07]
  5 studies · 317 participants
  Low

LNG‐IUS vs non‐intrauterine progestogen

It is very uncertain whether LNG‐IUS changes satisfaction with treatment compared with non‐intrauterine progestogen (very low certainty).

• Levonorgestrel‐releasing intrauterine system for endometrial hyperplasia 2020 · Cochrane Headline outcomes only
  OR 5.28 [2.51, 11.1]
  2 studies · 202 participants
  Very low

Postoperative use of LNG‐IUD vs postoperative GnRH‐a

The review found no eligible studies for this question.

• Levonorgestrel‐releasing intrauterine device (LNG‐IUD) for symptomatic endometriosis following surgery 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Postoperative use of LNG‐IUD vs expectant management

• Levonorgestrel‐releasing intrauterine device (LNG‐IUD) for symptomatic endometriosis following surgery 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 95 participants
  Very low