Findings

What do systematic reviews say?

10 questions · 10 findings · 1 reviews · Anaesthesia

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No studies found 0 · 0%GRADE not reported 2 · 20%Very low 8 · 80%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Lidocaine IV vs placebo or no treatment

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults undergoing surgery with general anaesthesia

1 finding from 1 review

Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
29 studies · 1656 participants
Very low

Lidocaine IV vs thoracic epidural blockade

Postoperative opioid consumption, 'overall' (MEQ, mg) · adults undergoing surgery with general anaesthesia

1 finding from 1 review

Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Lidocaine IV vs placebo or no treatment

Gastrointestinal recovery · adults undergoing surgery with general anaesthesia

It is very uncertain whether intravenous (IV) lidocaine changes gastrointestinal recovery compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery in adults 2018 · Cochrane Headline outcomes only
RR 0.37 [0.15, 0.87]
4 studies · 273 participants
Very low

Lidocaine IV vs placebo or no treatment

Adverse events (e.g. the number of participants that died, or had arrhythmias, other heart rate disorders, or showed any signs of lidocaine toxicity) · adults undergoing surgery with general anaesthesia

1 finding from 1 review

Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Lidocaine IV vs placebo or no treatment

Nausea · adults undergoing surgery with general anaesthesia

It is very uncertain whether intravenous (IV) lidocaine changes postoperative nausea, 'overall' (0 to 24 h, to 48 h, to 72 h) compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery in adults 2018 · Cochrane Headline outcomes only
RR 0.78 [0.67, 0.91]
35 studies · 1903 participants
Very low

Lidocaine IV vs placebo or no treatment

Postoperative opioid consumption, 'overall' (MEQ, mg) · adults undergoing surgery with general anaesthesia

1 finding from 1 review

Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
40 studies · 2201 participants
Very low

Lidocaine IV vs thoracic epidural blockade

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults undergoing surgery with general anaesthesia

1 finding from 1 review

Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Lidocaine IV vs thoracic epidural blockade

Gastrointestinal recovery · adults undergoing surgery with general anaesthesia

1 finding from 1 review

Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low

Lidocaine IV vs thoracic epidural blockade

1 finding from 1 review

Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Lidocaine IV vs thoracic epidural blockade

Nausea · adults undergoing surgery with general anaesthesia

1 finding from 1 review

Continuous intravenous perioperative lidocaine infusion for postoperative pain and recovery in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 60 participants
Very low