Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

19 questions · 19 findings · 3 reviews · Skin

No studies found 12 · 63.2%GRADE not reported 0 · 0%Very low 4 · 21.1%Low 3 · 15.8%Moderate 0 · 0%High 0 · 0%

Intravenous soya oil‐derived (n‐6) fatty acid‐based lipid emulsion vs intravenous fish oil‐derived (n‐3) fatty acid‐based lipid emulsion

Proportion of participants achieving clear or almost clear skin (PASI 90 to 100 or PGA 0 to 1) · guttate psoriasis

The review found no eligible studies for this question.

1 finding from 1 review

Intravenous soya oil‐derived (n‐6) fatty acid‐based lipid emulsion vs intravenous fish oil‐derived (n‐3) fatty acid‐based lipid emulsion

Percentage of participants with adverse effects and severe adverse effects · guttate psoriasis

The review found no eligible studies for this question.

1 finding from 1 review

Intravenous soya oil‐derived (n‐6) fatty acid‐based lipid emulsion vs intravenous fish oil‐derived (n‐3) fatty acid‐based lipid emulsion

Number of relapses of guttate psoriasis or flares within a period of 6 months after the treatment has finished · guttate psoriasis

The review found no eligible studies for this question.

1 finding from 1 review

Intravenous soya oil‐derived (n‐6) fatty acid‐based lipid emulsion vs intravenous fish oil‐derived (n‐3) fatty acid‐based lipid emulsion

Proportion of participants achieving PASI 75 or PGA 1 to 2 · guttate psoriasis

The review found no eligible studies for this question.

1 finding from 1 review

Intravenous soya oil‐derived (n‐6) fatty acid‐based lipid emulsion vs intravenous fish oil‐derived (n‐3) fatty acid‐based lipid emulsion

Improvement in participant satisfaction measures and quality of life assessment measures Overall subjective score on 5 items (appearance of lesions, impairment of daily life, pruritus, burning, and pain) reported through figures · guttate psoriasis
1 finding from 1 review

IVIg vs no IVIG

Disease‐specific mortality ‐ SJS and TEN (time to · Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN overlap syndrome

It is very uncertain whether intravenous immunoglobulin (IVIG) changes SJS/TEN‐specific mortality (time to compared with no IVIG (very low certainty).

1 finding from 1 review