Adverse events (e.g. the number of participants that died, or had arrhythmias, other heart rate disorders, or showed any signs of lidocaine toxicity) · adults undergoing surgery with general anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Nausea · adults undergoing surgery with general anaesthesia
1 finding from 1 review
Ulcer healing · patients with Buerger's disease
It is very uncertain whether intravenous prostacyclin analogue changes ulcer healing compared with intravenous prostaglandin analogue (very low certainty).
1 finding from 1 review
Complete relief of pain · patients with Buerger's disease
Intravenous prostacyclin analogue showed no clear difference in complete relief of pain compared with intravenous prostaglandin analogue (low certainty).
1 finding from 1 review
Rate of amputation · patients with Buerger's disease
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
All‐cause mortality · people with paracetamol (acetaminophen) overdose
1 finding from 1 review
Hepatotoxicity · people with paracetamol (acetaminophen) overdose
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Behaviour · Children and adolescents (0 to 16 years) needing dental treatment
1 finding from 1 review
Behaviour · Children and adolescents (0 to 16 years) needing dental treatment
It is very uncertain whether intravenous midazolam changes behaviour (Houpt/behavioural score) compared with placebo (including no intervention) (very low certainty).
1 finding from 1 review
Level of sedation on a sedation assessment scale · adults and children requiring sedation before gastrointestinal endoscopy and bronchoscopy
1 finding from 1 review
Incomplete procedure · adults requiring sedation before gastrointestinal endoscopy and bronchoscopy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Anterograde amnesia (defined by number of participants who recalled the procedure) · adults requiring sedation before gastrointestinal endoscopy and bronchoscopy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Disinhibition or excitation · adults requiring sedation before gastrointestinal endoscopy and bronchoscopy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Discomfort/pain · adults requiring sedation before gastrointestinal endoscopy and bronchoscopy
1 finding from 1 review
Allergic or anaphylactoid reaction · adults requiring sedation before gastrointestinal endoscopy and bronchoscopy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Anxiety · adults and children requiring sedation before gastrointestinal endoscopy and bronchoscopy
Intravenous midazolam showed no clear difference in numeric rating of anxiety or rated as anxious compared with diazepam (low certainty).
1 finding from 1 review
Incomplete procedure · adults and children requiring sedation before gastrointestinal endoscopy and bronchoscopy
1 finding from 1 review
Anterograde amnesia (defined by number of participants who recalled the procedure) · adults and children requiring sedation before gastrointestinal endoscopy and bronchoscopy
Intravenous midazolam may leads to lower anterograde amnesia (defined by number of participants who recalled… compared with diazepam (low certainty).
1 finding from 1 review
Disinhibition or excitation · adults and children requiring sedation before gastrointestinal endoscopy and bronchoscopy
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Discomfort/pain · adults and children requiring sedation before gastrointestinal endoscopy and bronchoscopy
Intravenous midazolam showed no clear difference in discomfort/pain compared with diazepam (low certainty).
1 finding from 1 review