What do systematic reviews say?

Intraperitoneal vs oral calcitriol

Intraperitoneal showed no clear difference in abnormal bone histology Bone biopsy compared with oral calcitriol (low certainty).

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  RR 1.06 [0.7, 1.61]
  1 study · 33 participants
  Low

Intraperitoneal vs oral calcitriol

Intraperitoneal showed no clear difference in adynamic bone disease Bone histology compared with oral calcitriol (low certainty).

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  RR 1.49 [0.59, 3.74]
  1 study · 33 participants
  Low

Intraperitoneal vs oral calcitriol

Intraperitoneal showed no clear difference in osteitis fibrosa Bone histology compared with oral calcitriol (low certainty).

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  RR 0.35 [0.08, 1.51]
  1 study · 33 participants
  Low

Intraperitoneal vs oral calcitriol

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 33 participants
  Low

Intraperitoneal vs oral calcitriol

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 33 participants
  Low

Intraperitoneal vs oral calcitriol

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 33 participants
  Low

Intraperitoneal vs oral calcitriol

• Interventions for bone disease in children with chronic kidney disease 2010 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 21 participants
  Low

Oral or topical or intraperitoneal antibiotics vs placebo/no treatment

Oral or topical or intraperitoneal antibiotics showed no clear difference in peritonitis (number of patients with one or more episodes) compared with placebo/no treatment (low certainty).

• Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients 2017 · Cochrane Headline outcomes only
  RR 0.82 [0.57, 1.19]
  5 studies · 395 participants
  Low

Oral or topical or intraperitoneal antibiotics vs placebo/no treatment

Oral or topical or intraperitoneal antibiotics showed no clear difference in exit‐site/tunnel infection (number of patients with one or more… compared with placebo/no treatment (low certainty).

• Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients 2017 · Cochrane Headline outcomes only
  RR 0.45 [0.19, 1.04]
  3 studies · 191 participants
  Low

Oral or topical or intraperitoneal antibiotics vs placebo/no treatment

Oral or topical or intraperitoneal antibiotics showed no clear difference in catheter removal or replacement (number of patients) compared with placebo/no treatment (low certainty).

• Antimicrobial agents for preventing peritonitis in peritoneal dialysis patients 2017 · Cochrane Headline outcomes only
  RR 0.82 [0.46, 1.46]
  5 studies · 395 participants
  Low