Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

242 questions · 251 findings · 27 reviews

No studies found 44 · 17.5%GRADE not reported 3 · 1.2%Very low 69 · 27.5%Low 70 · 27.9%Moderate 52 · 20.7%High 13 · 5.2%

Outcomes for all interventions for smoking cessation in pregnancy vs control: subgrouped by main intervention strategy (comparison 20)

Abstinence · Pregnant women who smoke

Outcomes for all interventions for smoking cessation in pregnancy leads to higher abstinence at 0 to 5 months postpartum compared with control: subgrouped by main intervention strategy (comparison 20) (high certainty).

2 findings from 1 review

Outcomes for all interventions for smoking cessation in pregnancy vs control: subgrouped by main intervention strategy (comparison 20)

Birthweight < 2500 (g) · Pregnant women who smoke

Outcomes for all interventions for smoking cessation in pregnancy leads to lower low birthweight (under 2500 g) compared with control: subgrouped by main intervention strategy (comparison 20) (high certainty).

1 finding from 1 review

Outcomes for all interventions for smoking cessation in pregnancy vs control: subgrouped by main intervention strategy (comparison 20)

Gestational age (preterm birth < 37 weeks) · Pregnant women who smoke

Outcomes for all interventions for smoking cessation in pregnancy showed no clear difference in preterm birth (under 37 weeks) compared with control: subgrouped by main intervention strategy (comparison 20) (high certainty).

1 finding from 1 review

Outcomes for all interventions for smoking cessation in pregnancy vs control: subgrouped by main intervention strategy (comparison 20)

Mean birthweight · Pregnant women who smoke

Outcomes for all interventions for smoking cessation in pregnancy showed no clear difference in mean birthweight (g) compared with control: subgrouped by main intervention strategy (comparison 20) (high certainty).

1 finding from 1 review

Outcomes for all interventions for smoking cessation in pregnancy vs control: subgrouped by main intervention strategy (comparison 20)

Stillbirth · Pregnant women who smoke

Outcomes for all interventions for smoking cessation in pregnancy showed no clear difference in stillbirths compared with control: subgrouped by main intervention strategy (comparison 20) (high certainty).

1 finding from 1 review

Outcomes for all interventions for smoking cessation in pregnancy vs control: subgrouped by main intervention strategy (comparison 20)

Admission to NICU (primary outcome)№ of participants: 204(1 RCT) · Pregnant women who smoke

Outcomes for all interventions for smoking cessation in pregnancy leads to lower NICU admissions compared with control: subgrouped by main intervention strategy (comparison 20) (high certainty).

1 finding from 1 review

Psychological interventions (positive and negative reinforcement) vs no treatment

Sucking cessation (long term) · Children with a non-nutritive sucking habit (digit or pacifier)

Psychological interventions (positive and negative reinforcement) led to higher sucking cessation (long term) compared with no treatment; GRADE not reported.

1 finding from 1 review

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Loop ligation of myoma pseudocapsule plus vasopressin · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in loop ligation of myoma pseudocapsule plus vasopressin compared with placebo or no treatment (low certainty).

1 finding from 1 review

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Fibrin sealant patch (collagen sponge with thrombin and fibrinogen) · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in fibrin sealant patch (collagen sponge with thrombin and fibrinogen) compared with placebo or no treatment (low certainty).

1 finding from 1 review

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Misoprostol in abdominal myomectomy · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in misoprostol in abdominal myomectomy compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Misoprostol in laparoscopic myomectomy · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in misoprostol in laparoscopic myomectomy compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Bupivicaine plus epinephrine · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in bupivicaine plus epinephrine compared with placebo or no treatment (low certainty).

1 finding from 1 review

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Intravenous injection of tranexamic acid · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in intravenous injection of tranexamic acid compared with placebo or no treatment (low certainty).

1 finding from 1 review

Interventions to reduce blood loss during myomectomy for fibroids vs placebo or no treatment

Gelatin‐thrombin matrix · women with uterine fibroids

Interventions to reduce blood loss during myomectomy for fibroids showed no clear difference in gelatin‐thrombin matrix compared with placebo or no treatment (low certainty).

1 finding from 1 review