Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

46 questions · 58 findings · 6 reviews · Hepato-Biliary

No studies found 6 · 10.3%GRADE not reported 0 · 0%Very low 52 · 89.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Intervention vs no intervention or control intervention (control)

Chronic HCV infection†‐ interferon‐alpha versus no intervention · people with acute hepatitis C infection

It is very uncertain whether intervention changes chronic HCV infection†‐ interferon‐alpha versus no intervention compared with no intervention or control intervention (control) (very low certainty).

1 finding from 1 review

Intervention vs no intervention or control intervention (control)

Chronic HCV infection†‐ interferon‐beta versus no intervention · people with acute hepatitis C infection

It is very uncertain whether intervention changes chronic HCV infection†‐ interferon‐beta versus no intervention compared with no intervention or control intervention (control) (very low certainty).

1 finding from 1 review

Intervention vs no intervention or control intervention (control)

Chronic HCV infection†‐ MTH‐68/B vaccine versus no intervention · people with acute hepatitis C infection

It is very uncertain whether intervention changes chronic HCV infection†‐ MTH‐68/B vaccine versus no intervention compared with no intervention or control intervention (control) (very low certainty).

1 finding from 1 review

Intervention vs no intervention or control intervention (control)

Adverse events (proportion) ‐ interferon‐alpha versus no intervention · people with acute hepatitis C infection

It is very uncertain whether intervention changes adverse events (proportion) ‐ interferon‐alpha versus no intervention compared with no intervention or control intervention (control) (very low certainty).

1 finding from 1 review

Intervention vs no intervention or control intervention (control)

Adverse events (number) ‐ interferon‐beta versus no intervention · people with acute hepatitis C infection

It is very uncertain whether intervention changes adverse events (proportion) ‐ interferon‐beta versus no intervention compared with no intervention or control intervention (control) (very low certainty).

2 findings from 1 review

Intervention vs no intervention or control intervention (control)

Serious adverse events (number) ‐ pegylated interferon‐alpha plus ribavirin versus pegylated interferon‐alpha · people with acute hepatitis C infection

It is very uncertain whether intervention changes serious adverse events (proportion) ‐ pegylated interferon‐alpha… compared with no intervention or control intervention (control) (very low certainty).

2 findings from 1 review

Intervention vs no intervention or control intervention (control)

Chronic HCV infection†‐ pegylated interferon‐alpha plus ribavirin versus pegylated interferon‐alpha · people with acute hepatitis C infection

It is very uncertain whether intervention changes chronic HCV infection†‐ pegylated interferon‐alpha plus ribavirin… compared with no intervention or control intervention (control) (very low certainty).

1 finding from 1 review

Intervention vs control

Selective bowel decontamination versus inactive control · people undergoing liver transplantation

It is very uncertain whether intervention changes selective bowel decontamination versus inactive control compared with control (very low certainty).

2 findings from 1 review

Intervention vs control

Granulocyte‐colony stimulating factor (G‐CSF) versus placebo · people undergoing liver transplantation

It is very uncertain whether intervention changes granulocyte‐colony stimulating factor (G‐CSF) versus placebo compared with control (very low certainty).

2 findings from 1 review

Intervention vs control

Selective bowel decontamination versus prebiotics with probiotics · people undergoing liver transplantation
2 findings from 1 review

Intervention vs control

Selective bowel decontamination versus prebiotics · people undergoing liver transplantation
2 findings from 1 review

Intervention vs control

Prebiotics with probiotics versus prebiotics · people undergoing liver transplantation
2 findings from 1 review