evidencegaps
Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

3,024 questions · 3,338 findings · 330 reviews

Sort:Best matchNewestHighest certaintyDownload CSV
No studies found 735 · 22%GRADE not reported 282 · 8.4%Very low 962 · 28.8%Low 870 · 26.1%Moderate 384 · 11.5%High 105 · 3.1%

Adverse event outcomes for dietary combined with physical activity interventions vs standard‐of‐care therapy

Neonatal hypoglycaemia · pregnant women, excluding women already diagnosed with GDM in this pregnancy and those with pre‐existing diabetes mellitus

Combined diet and exercise interventions showed no clear difference in neonatal hypoglycaemia compared with standard care (child) (low certainty).

1 finding from 1 review

Adverse event outcomes for dietary combined with physical activity interventions vs standard‐of‐care therapy

Z score BMI · pregnant women, excluding women already diagnosed with GDM in this pregnancy and those with pre‐existing diabetes mellitus

Combined diet and exercise interventions showed no clear difference in childhood adiposity (latest time reported) (BMI z score) compared with standard care (child) (low certainty).

1 finding from 1 review

Adverse event outcomes for dietary combined with physical activity interventions vs standard‐of‐care therapy

Type 2 diabetes mellitus · pregnant women, excluding women already diagnosed with GDM in this pregnancy and those with pre‐existing diabetes mellitus
2 findings from 1 review

Adverse event outcomes for dietary combined with physical activity interventions vs standard‐of‐care therapy

Hypertensive disorders of pregnancy: pre‐eclampsia · pregnant women, excluding women already diagnosed with GDM in this pregnancy and those with pre‐existing diabetes mellitus

Combined diet and exercise interventions showed no clear difference in hypertensive disorders of pregnancy (pre‐eclampsia) compared with standard care (mother) (low certainty).

1 finding from 1 review

Adverse event outcomes for dietary combined with physical activity interventions vs standard‐of‐care therapy

Hypertensive disorders of pregnancy (pregnancy‐induced hypertension) · pregnant women, excluding women already diagnosed with GDM in this pregnancy and those with pre‐existing diabetes mellitus

It is very uncertain whether combined diet and exercise interventions changes hypertensive disorders of pregnancy (pregnancy‐induced… compared with standard care (mother) (very low certainty).

1 finding from 1 review

Adverse event outcomes for dietary combined with physical activity interventions vs standard‐of‐care therapy

Caesarean section · pregnant women, excluding women already diagnosed with GDM in this pregnancy and those with pre‐existing diabetes mellitus

Combined diet and exercise interventions showed no clear difference in caesarean section compared with standard care (mother) (moderate certainty).

1 finding from 1 review

Adverse event outcomes for dietary combined with physical activity interventions vs standard‐of‐care therapy

Perineal trauma · pregnant women, excluding women already diagnosed with GDM in this pregnancy and those with pre‐existing diabetes mellitus

Combined diet and exercise interventions showed no clear difference in perineal trauma compared with standard care (mother) (moderate certainty).

1 finding from 1 review

Adverse event outcomes for dietary combined with physical activity interventions vs standard‐of‐care therapy

Gestational weight gain · pregnant women, excluding women already diagnosed with GDM in this pregnancy and those with pre‐existing diabetes mellitus

Combined diet and exercise interventions showed no clear difference in gestational weight gain (kg) compared with standard care (mother) (moderate certainty).

1 finding from 1 review

Adverse event outcomes for dietary combined with physical activity interventions vs standard‐of‐care therapy

Perinatal mortality · pregnant women, excluding women already diagnosed with GDM in this pregnancy and those with pre‐existing diabetes mellitus

Combined diet and exercise interventions showed no clear difference in perinatal mortality compared with standard care (child) (low certainty).

1 finding from 1 review

Cessation interventions with a partner support component vs cessation interventions without a partner support component

Long‐term smoking abstinence (6 to 9 months) · people who smoked and were willing to be recruited to a cessation programme

Cessation interventions with a partner support component showed no clear difference in long‐term smoking abstinence (6 to 9 months) compared with cessation interventions without a partner support component (low certainty).

1 finding from 1 review

Cessation interventions with a partner support component vs cessation interventions without a partner support component

Long‐term smoking abstinence (12 months+) · people who smoked and were willing to be recruited to a cessation programme

Cessation interventions with a partner support component showed no clear difference in long‐term smoking abstinence (12 months+) compared with cessation interventions without a partner support component (low certainty).

1 finding from 1 review

Comprehensive oral health intervention (oral health education plus additional support: motivational interviewing, toothbrush/toothpaste provision, community engagement, and/or fluoride varnish/sealant application) delivered by non-dental health workers vs control (no intervention/usual care/isotonic exercise)

Caries experience at the surface level (dmfs/defs) · Children (mean age newborn to ~5.2 years) and their parents/carers

Comprehensive interventions produced a small, statistically significant reduction in surface-level caries (dmfs SMD -0.14, 95% CI -0.26 to -0.02; 10 studies; not GRADE-rated).

1 finding from 1 review

Comprehensive oral health intervention (oral health education plus additional support: motivational interviewing, toothbrush/toothpaste provision, community engagement, and/or fluoride varnish/sealant application) delivered by non-dental health workers vs control (no intervention/usual care/isotonic exercise)

Caries experience · Children (mean age newborn to ~5.2 years) and their parents/carers

Comprehensive interventions produced a statistically significant reduction in tooth-level caries (dmft SMD -0.47, 95% CI -0.84 to -0.10; 4 studies; not GRADE-rated), though heterogeneity was very high.

1 finding from 1 review

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

Treatment time · Participants who previously underwent orthodontic treatment, with subsequent crowding (relapse) of the lower front teeth (lower incisors…

The review found no eligible studies for this question.

1 finding from 1 review

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

Cost-benefit consideration · Participants who previously underwent orthodontic treatment, with subsequent crowding (relapse) of the lower front teeth (lower incisors…

The review found no eligible studies for this question.

1 finding from 1 review

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

Patient discomfort · Participants who previously underwent orthodontic treatment, with subsequent crowding (relapse) of the lower front teeth (lower incisors…

The review found no eligible studies for this question.

1 finding from 1 review

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

Stability of the correction · Participants who previously underwent orthodontic treatment, with subsequent crowding (relapse) of the lower front teeth (lower incisors…

The review found no eligible studies for this question.

1 finding from 1 review

Any intervention to manage relapse: fixed options (labial braces, lingual braces, fixed lingual wire) or removable options (Hawley's retainer with spring elastomeric module, Bloore removable aligner, other Hawley's retainer modifications, Invisalign, Clearstep) vs no intervention or another intervention

Quality of life · Participants who previously underwent orthodontic treatment, with subsequent crowding (relapse) of the lower front teeth (lower incisors…

The review found no eligible studies for this question.

1 finding from 1 review