Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,486 questions · 2,727 findings · 268 reviews

No studies found 600 · 22%GRADE not reported 229 · 8.4%Very low 789 · 28.9%Low 707 · 25.9%Moderate 314 · 11.5%High 88 · 3.2%

Any of the interventions (CR, SE, SW, sealing with sealant materials, Hall Technique, or NRCC) vs Each other, placebo, or no treatment

Adverse events (any type) and safety of sealant · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…

The review found no eligible studies for this question.

1 finding from 1 review

Any of the interventions (CR, SE, SW, sealing with sealant materials, Hall Technique, or NRCC) vs Each other, placebo, or no treatment

Subjective evaluation of the treatments by participants · Children and/or adults with permanent or primary teeth, vital (sensitive) pulps, and cavitated or dentine carious lesions conventionally…

The review found no eligible studies for this question.

1 finding from 1 review

Comparison 2: interventions for patients with multiple episodes of SH or emerging personality problems vs treatment

Repetition of SH at post‐intervention · children and adolescents who engage in SH.

Comparison 2: interventions for patients with multiple episodes of… showed no clear difference in repetition of SH at post‐intervention compared with treatment (low certainty).

1 finding from 1 review

ANY FAMILY BASED INTERVENTIONS (>5 sessions) vs usual care

Social functioning: Specific ‐ unemployed ‐ at about 1 year · patients with schizophrenia

ANY FAMILY BASED INTERVENTIONS (>5 sessions) showed no clear difference in social functioning: Specific ‐ unemployed ‐ at about 1 year compared with STANDARD CARE (low certainty).

1 finding from 1 review

ANY FAMILY BASED INTERVENTIONS (>5 sessions) vs usual care

Social functioning: Specific ‐ unable to live independently ‐ at about 1 year · patients with schizophrenia

ANY FAMILY BASED INTERVENTIONS (>5 sessions) showed no clear difference in social functioning: Specific ‐ unable to live independently ‐ at… compared with STANDARD CARE (low certainty).

1 finding from 1 review

ANY FAMILY BASED INTERVENTIONS (>5 sessions) vs usual care

Family outcome: Burden ‐ not improved/worse (objective burden related to self‐sufficiency) · patients with schizophrenia

It is very uncertain whether ANY FAMILY BASED INTERVENTIONS (>5 sessions) changes family outcome: Burden ‐ not improved/worse (objective burden… compared with STANDARD CARE (very low certainty).

1 finding from 1 review

Lay health worker‐led interventions for adult patients with harmful or hazardous alcohol or substance use vs enhanced usual care

Clinical recovery ‐ harmful or hazardous alcohol use (1 to 6 months post intervention) · adult patients with harmful or hazardous alcohol or substance use

Lay health worker‐led interventions for adult patients with harmful… showed no clear difference in clinical recovery ‐ harmful or hazardous alcohol use (1 to 6 months… compared with enhanced usual care (low certainty).

1 finding from 1 review

Lay health worker‐led interventions for adult patients with harmful or hazardous alcohol or substance use vs enhanced usual care

Prevalence of methamphetamine use (1 to 6 months post intervention) (RR < 1 denotes lower prevalence compared to control) · adult patients with harmful or hazardous alcohol or substance use

Lay health worker‐led interventions for adult patients with harmful… showed no clear difference in prevalence of methamphetamine use (1 to 6 months post intervention)… compared with enhanced usual care (low certainty).

1 finding from 1 review

Lay health worker‐led interventions for adult patients with harmful or hazardous alcohol or substance use vs enhanced usual care

Clinical symptoms ‐ alcohol use (1 to 6 months post intervention) ‐ risk of hazardous or harmful alcohol use · adult patients with harmful or hazardous alcohol or substance use
1 finding from 1 review

Lay health worker‐led interventions for adult patients with harmful or hazardous alcohol or substance use vs enhanced usual care

Clinical symptoms ‐ alcohol and substance use (1 to 6 months post intervention) · adult patients with harmful or hazardous alcohol or substance use
1 finding from 1 review