Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,024 questions · 3,338 findings · 330 reviews

No studies found 735 · 22%GRADE not reported 282 · 8.4%Very low 962 · 28.8%Low 870 · 26.1%Moderate 384 · 11.5%High 105 · 3.1%

Group B antipsychotic drugs: olanzapine + supportive intervention vs placebo or supportive treatment

Prodromal symptoms: transition to psychosis Endpoint data (events) · people in the prodromal stage of psychosis

It is very uncertain whether group B antipsychotic drugs: olanzapine + supportive intervention changes prodromal symptoms: transition to psychosis Endpoint data, (events)… compared with placebo + supportive intervention (very low certainty).

1 finding from 1 review

Group B antipsychotic drugs: olanzapine + supportive intervention vs placebo or supportive treatment

Satisfaction and acceptability of treatment (medium term) ‐ leaving the study early · people in the prodromal stage of psychosis

It is very uncertain whether group B antipsychotic drugs: olanzapine + supportive intervention changes satisfaction with treatment: leaving the study early Endpoint data… compared with placebo + supportive intervention (very low certainty).

1 finding from 1 review

Outcomes for all interventions for smoking cessation in pregnancy vs control: subgrouped by main intervention strategy (comparison 20)

Abstinence · Pregnant women who smoke

Outcomes for all interventions for smoking cessation in pregnancy leads to higher abstinence at 0 to 5 months postpartum compared with control: subgrouped by main intervention strategy (comparison 20) (high certainty).

2 findings from 1 review

Outcomes for all interventions for smoking cessation in pregnancy vs control: subgrouped by main intervention strategy (comparison 20)

Birthweight < 2500 (g) · Pregnant women who smoke

Outcomes for all interventions for smoking cessation in pregnancy leads to lower low birthweight (under 2500 g) compared with control: subgrouped by main intervention strategy (comparison 20) (high certainty).

1 finding from 1 review

Outcomes for all interventions for smoking cessation in pregnancy vs control: subgrouped by main intervention strategy (comparison 20)

Gestational age (preterm birth < 37 weeks) · Pregnant women who smoke

Outcomes for all interventions for smoking cessation in pregnancy showed no clear difference in preterm birth (under 37 weeks) compared with control: subgrouped by main intervention strategy (comparison 20) (high certainty).

1 finding from 1 review

Outcomes for all interventions for smoking cessation in pregnancy vs control: subgrouped by main intervention strategy (comparison 20)

Mean birthweight · Pregnant women who smoke

Outcomes for all interventions for smoking cessation in pregnancy showed no clear difference in mean birthweight (g) compared with control: subgrouped by main intervention strategy (comparison 20) (high certainty).

1 finding from 1 review