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What do systematic reviews say?

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Evidence found and GRADE certainty

238 questions · 259 findings · 27 reviews

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No studies found 65 · 25.1%GRADE not reported 21 · 8.1%Very low 67 · 25.9%Low 55 · 21.2%Moderate 45 · 17.4%High 6 · 2.3%

Multi‐component interventions (with telehealth as a component of care) vs usual care

Number of people experiencing at least 1 exacerbation/moderate to severe exacerbation · patients with chronic obstructive pulmonary disease

It is very uncertain whether multi‐component interventions (with telehealth as a component of care) changes number of people experiencing at least 1 exacerbation/moderate to… compared with usual care (very low certainty).

1 finding from 1 review

Multi‐component interventions (with telehealth as a component of care) vs usual care

Time to first exacerbation · patients with chronic obstructive pulmonary disease

It is very uncertain whether multi‐component interventions (with telehealth as a component of care) changes time to first exacerbation compared with usual care (very low certainty).

1 finding from 1 review

Multi‐component interventions (with telehealth as a component of care) vs usual care

QoL · patients with chronic obstructive pulmonary disease
3 findings from 1 review

Multi‐component interventions (with telehealth as a component of care) vs usual care

Transmission‐related outcomes: hospitalization ‐ Number or proportion of hospital admissions · patients with chronic obstructive pulmonary disease

Multi‐component interventions (with telehealth as a component of care) showed no clear difference in number of people who had at least 1 hospital admission compared with usual care (low certainty).

1 finding from 1 review

Multi‐component interventions (with telehealth as a component of care) vs usual care

Number of people re‐admitted (all‐cause) · patients with chronic obstructive pulmonary disease

Multi‐component interventions (with telehealth as a component of care) probably leads to lower number of people re‐admitted (all‐cause) compared with usual care (moderate certainty).

1 finding from 1 review

Multi‐component interventions (with telehealth as a component of care) vs usual care

Anti‐cytokine, all‐cause mortality ‐ uncertain risk of bias · patients with chronic obstructive pulmonary disease

It is very uncertain whether multi‐component interventions (with telehealth as a component of care) changes mortality (all‐cause) overall analysis compared with usual care (very low certainty).

1 finding from 1 review

Multi‐component interventions (with telehealth as a component of care) vs usual care

Adverse events: number of people with 1 or more (all‐cause) · patients with chronic obstructive pulmonary disease

It is very uncertain whether multi‐component interventions (with telehealth as a component of care) changes adverse events: number of people with 1 or more (all‐cause) compared with usual care (very low certainty).

1 finding from 1 review

Digital intervention with or without routine supported self‐management vs control

Self‐efficacy · the management of chronic obstructive pulmonary disease
2 findings from 1 review

Self‐management interventions vs usual care

Courses of oral corticosteroids · patients with chronic obstructive pulmonary disease

Self‐management interventions including action plans for exacerbations showed no clear difference in courses of oral steroids compared with usual care (low certainty).

1 finding from 1 review