Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,486 questions · 2,727 findings · 268 reviews

No studies found 600 · 22%GRADE not reported 229 · 8.4%Very low 789 · 28.9%Low 707 · 25.9%Moderate 314 · 11.5%High 88 · 3.2%

Any antifungal intervention for the treatment of oral candidiasis vs Placebo, no treatment, or another active antifungal intervention

Relief of dysphagia · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis

The review found no eligible studies for this question.

1 finding from 1 review

Any antifungal intervention for the treatment of oral candidiasis vs Placebo, no treatment, or another active antifungal intervention

Relief of pain · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis

The review found no eligible studies for this question.

1 finding from 1 review

Any antifungal intervention for the treatment of oral candidiasis vs Placebo, no treatment, or another active antifungal intervention

Patient quality of life · Patients with cancer receiving chemotherapy and/or radiotherapy with overt oral candidiasis

The review found no eligible studies for this question.

1 finding from 1 review

Single‐component medication monitoring and adjustment intervention vs control

Incidence of delirium · people at risk of delirium in institutional long‐term care

Single‐component medication monitoring and adjustment intervention probably leads to lower incidence of delirium NH‐CAM compared with control (moderate certainty).

1 finding from 1 review

Single‐component medication monitoring and adjustment intervention vs control

All‐cause mortality · people at risk of delirium in institutional long‐term care

Single‐component medication monitoring and adjustment intervention showed no clear difference in mortality compared with control (moderate certainty).

1 finding from 1 review

Single‐component medication monitoring and adjustment intervention vs control

Falls · people at risk of delirium in institutional long‐term care

Single‐component medication monitoring and adjustment intervention showed no clear difference in falls Fall events compared with control (low certainty).

1 finding from 1 review

Single‐component medication monitoring and adjustment intervention vs control

Hospital admissions · people at risk of delirium in institutional long‐term care

Single‐component medication monitoring and adjustment intervention showed no clear difference in hospital admissions compared with control (moderate certainty).

1 finding from 1 review

Pharmacological intervention and a form of psychotherapy (combination) vs pharmacological intervention and usual care or attention control (single)

Depression: meeting study criteria for depression at end of · people with depression after stroke
2 findings from 1 review

Pharmacological intervention and a form of psychotherapy (combination) vs pharmacological intervention and usual care or attention control (single)

Depression: < 50% reduction in scale scores at end of treatment (primary outcome) · people with depression after stroke
1 finding from 1 review

Psychological intervention (habit reversal / positive reinforcement) vs Alternative psychological intervention (DRO / negative reinforcement)

Sucking cessation (short term) · Children with a non-nutritive sucking habit (digit or pacifier)
1 finding from 1 review
  • Interventions for the cessation of non‐nutritive sucking habits in children 2015 · Cochrane All outcomes
    Short term (less than 12 months)
    Christensen 1987 (20 participants) compared habit reversal (HR) with differential reinforcement of other behaviour (DRO): no statistically significant difference. Larsson 1972 (38 participants) compared positive with…
    2 studies · 58 participants
    GRADE not reported

Digital intervention with or without routine supported self‐management vs control

Self‐efficacy · the management of chronic obstructive pulmonary disease
2 findings from 1 review